# Side effects of metal-based dental implantology treatment - A review

**Authors:** Deepesh Kumar Gupta, Shubham Sethi, Anumeha Jha, Ambika Thakur, Khushbu Gupta

PMC · DOI: 10.6026/973206300214048 · Bioinformation · 2025-11-15

## TL;DR

This review discusses how titanium dental implants can corrode in the mouth, leading to health issues and implant failure.

## Contribution

The paper provides a comprehensive review of corrosion mechanisms and their clinical implications for titanium dental implants.

## Key findings

- Corrosion of titanium implants is influenced by factors like salivary pH and bacterial biofilms.
- Corrosion can lead to titanium ion release and local inflammation, increasing the risk of peri-implantitis.
- Understanding these mechanisms is crucial for improving the longevity of dental implants.

## Abstract

Titanium dental implants are widely used for their biocompatibility and mechanical strength but are vulnerable to corrosion within the
oral environment. Corrosive processes such as galvanic, pitting, crevice and fretting corrosion are influenced by salivary pH, fluoride
concentration, bacterial biofilms and mechanical forces. These factors can disrupt the protective oxide layer, leading to titanium ion
release, local inflammation, peri-implantitis and potential implant failure. Therefore, it is of interest to review the mechanisms and
clinical implications of titanium implant corrosion.

## Linked entities

- **Chemicals:** titanium (PubChem CID 23963), titanium ion (PubChem CID 23963), fluoride (PubChem CID 28179)

## Full-text entities

- **Diseases:** peri-implantitis (MESH:D057873), inflammation (MESH:D007249)
- **Chemicals:** fluoride (MESH:D005459), metal (MESH:D008670), oxide (MESH:D010087), Titanium (MESH:D014025)

## Full text

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## References

16 references — full list in the complete paper: https://tomesphere.com/paper/PMC12880166/full.md

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Source: https://tomesphere.com/paper/PMC12880166