# Comparative evaluation between boric acid and sodium hypochlorite in pulp dissolving ability: An in vitro study

**Authors:** Madhulika Singh, Anjali Gupta, Praveen Mishra, Abhishek Pal, Shruti Sharma, Shruti Kashyap

PMC · DOI: 10.6026/973206300214011 · Bioinformation · 2025-11-15

## TL;DR

This study compares how well boric acid and sodium hypochlorite dissolve pulp tissue in root canals.

## Contribution

The study provides a direct in vitro comparison of different concentrations of boric acid and sodium hypochlorite for pulp dissolving ability.

## Key findings

- 10% boric acid showed higher pulp dissolving ability than 5% boric acid.
- 5.25% sodium hypochlorite demonstrated significant pulp dissolving effectiveness.
- Weight loss measurements indicated varying efficacy among the tested solutions.

## Abstract

Thorough elimination of pulp tissue remnants and significant reduction of microbial pathogens within the root canal system are
essential for the success of endodontic treatment. Therefore, it is of interest to compare and assess the effectiveness of 10% boric acid,
5% boric acid and 5.25% NaOCl in dissolving pulp tissue. Forty pulp tissue samples obtained during routine endodontic procedures were
standardized to 25 mg each, evenly distributed into four groups (n=10 per group). The initial weight of the samples was recorded using an
analytical balance and each sample was then immersed in 5 ml of the respective solution for 30 minutes at room temperature. After
immersion, the samples were re-weighed and the weight loss was recorded and analyzed.

## Linked entities

- **Chemicals:** boric acid (PubChem CID 7628), sodium hypochlorite (PubChem CID 23665760), NaOCl (PubChem CID 23665760)

## Full-text entities

- **Diseases:** weight loss (MESH:D015431)
- **Chemicals:** NaOCl (MESH:D012973), boric acid (MESH:C032688)

## Full text

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12880145/full.md

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Source: https://tomesphere.com/paper/PMC12880145