# Serum calcium and magnesium in preeclampsia: A comparative study

## TL;DR

The study compares serum calcium and magnesium levels in preeclamptic and normotensive pregnant women to assess their role in predicting complications.

## Contribution

The study provides new evidence on electrolyte imbalances in preeclampsia and their potential use in antenatal screening.

## Key findings

- Preeclamptic women had significantly lower serum calcium and magnesium levels compared to normotensive women.
- Lower electrolyte levels were associated with higher rates of preterm birth, cesarean delivery, and NICU admissions.

## Abstract

Preeclampsia is a hypertensive disorder of pregnancy linked to endothelial dysfunction and electrolyte imbalance. Therefore, it is of
interest to evaluate serum calcium and magnesium levels in 100 preeclamptic and 100 normotensive pregnant women beyond 28 weeks gestation
at a tertiary hospital in Central India. Spectrophotometric analysis showed significantly lower calcium (7.84 ±0.74 mg/dL vs.
9.68 ±0.97 mg/dL; p<0.001) and magnesium levels (1.74 ±0.54 mg/dL vs. 1.88 ±0.76 mg/dL; p=0.040) in preeclamptic
women. Adverse outcomes such as preterm birth, cesarean delivery, and NICU admissions were more frequent in the preeclampsia group. These
findings suggest the utility of calcium and magnesium screening in antenatal care for early risk stratification and potential prevention
of complications.