# Mechanical properties of thermoformed and 3D-printed aligners after cleansing solution exposure: An in vitro study

**Authors:** Diksha Vinod Wali, Shashank Sharad Gaikwad, Vilasrao Kadam, Parag Vishnu Gangurde, Nityanand Shankar Shetty, Chinmay Mahale, Prakash Sarkar

PMC · DOI: 10.6026/973206300214212 · Bioinformation · 2025-11-15

## TL;DR

This study examines how cleaning solutions affect the mechanical properties of orthodontic aligners made from different materials.

## Contribution

The study provides new insights into the effects of specific cleaning agents on aligner materials.

## Key findings

- Peroxide-based cleaners significantly degrade aligner properties.
- Resin-based aligners show superior resistance to cleaning agents.
- Artificial saliva has minimal impact on mechanical properties.

## Abstract

The impact of common cleaning solutions on the mechanical properties of clear orthodontic aligners made from PET-G, polyurethane and
resin-based materials is of interest. Nanoindentation tests measured elastic modulus, hardness, elastic index and load relaxation after
exposure to Retainer Brite®, Fresh Guard® and artificial saliva. The results showed that peroxide-based cleaners significantly degrade
aligner properties, while Fresh Guard® causes moderate changes and artificial saliva has minimal effects. Resin-based aligners showed
superior chemical stability, making them more resistant to cleaning agents. Thus, mild cleaners are recommended for maintaining aligner
performance.

## Linked entities

- **Chemicals:** peroxide (PubChem CID 784)

## Full-text entities

- **Chemicals:** Retainer Brite (-), peroxide (MESH:D010545), PET-G (MESH:C066907), polyurethane (MESH:D011140)

## Full text

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12880138/full.md

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Source: https://tomesphere.com/paper/PMC12880138