# Splenic Metastasis in Ewing Sarcoma

**Authors:** Lucas Bijnens, Brecht Van Berkel, Maarten Steyvers

PMC · DOI: 10.5334/jbsr.4203 · Journal of the Belgian Society of Radiology · 2026-02-05

## TL;DR

This paper reports a rare case of Ewing sarcoma metastasizing to the spleen, highlighting the importance of considering rare metastases in patients with a history of the disease.

## Contribution

The paper presents the first reported case of splenic metastasis in Ewing sarcoma.

## Key findings

- A 20-year-old female with a history of Ewing sarcoma developed a splenic metastasis years after treatment.
- This case suggests that Ewing sarcoma can metastasize to the spleen, a site previously unreported in the literature.

## Abstract

Ewing sarcoma (ES) is a high-grade osseous malignancy that typically occurs between 10 and 20 years of age. Prognosis is poor with a 30% five-year survival in the case of metastatic disease. This case describes a 20-year-old female patient with known lumbar vertebral ES developing a splenic metastasis years after primary treatment. To the best of our knowledge, metastatic spread to the spleen in ES has not been reported before.

Teaching point: In patients with a history of Ewing sarcoma, new parenchymal lesions should always prompt consideration of rare metastatic disease, given its profound prognostic impact.

## Linked entities

- **Diseases:** Ewing sarcoma (MONDO:0012817)

## Full-text entities

- **Diseases:** Splenic Metastasis (MESH:D009362), ES (MESH:D012512), osseous malignancy (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12880045/full.md

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12880045/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12880045/full.md

---
Source: https://tomesphere.com/paper/PMC12880045