# Harnessing Microbial Volatile Organic Compounds for Crop Protection: Scientific Discovery, Bridging Ecological Function and On‐Farm Application

## TL;DR

This paper discusses how microbial volatile compounds can protect crops but need better research to work in real farming.

## Contribution

The paper proposes practical ways to bridge lab discoveries and field applications of microbial VOCs for crop protection.

## Key findings

- Most VOC studies lack validation in real plant or field conditions.
- There is limited understanding of VOC production consistency between lab and field.
- Ecological roles of VOCs can guide better field deployment strategies.

## Abstract

Microbial volatile organic compounds (VOCs) are integral to microbial ecological communication. Their potential as tools for sustainable crop protection is increasingly recognised, yet practical implementation remains limited. There are numerous in vitro lab‐based studies focussed on screening single strains of soil or plant‐associated microbes for their ability to produce VOCs and demonstrate their potential to inhibit plant pathogens or pests. Most of these, however, lack any validation in planta or in the field after petri dish experiments. This extends to a lack of understanding on whether the same VOCs are produced in vitro as in planta. How do we shift this focus and move from exciting lab‐based discoveries to practical, scalable crop protection solutions for farmers? This opinion piece explores the current state of research on microbial VOCs for crop protection, translational challenges in deploying them on‐farm, and highlights areas where learnings from the ecological roles of microbial VOCs can be leveraged towards field application.

This opinion article highlights how microbial VOCs can support sustainable crop protection and outlines the ecological, analytical and translational challenges that currently limit their field application. It proposes practical and technological pathways to bridge the gap between laboratory discoveries and on‐farm deployment.