# APSIC revised guidelines for prevention of central line associated bloodstream infections (CLABSI): a summary and position statement

**Authors:** Moi Lin Ling, Anucha Apisarnthanarak, Patricia Ching, Yee-Chun Chen, Glenys Harrington, Jin-Won Huh, Namita Jaggi, Keita Morikane, Sahadol Poonyathawon

PMC · DOI: 10.1017/ash.2026.10298 · Antimicrobial Stewardship & Healthcare Epidemiology : ASHE · 2026-02-03

## TL;DR

The revised APSIC guidelines provide updated strategies to prevent central line infections in healthcare settings, focusing on practical implementation and quality improvement.

## Contribution

The paper presents revised, practical guidelines tailored for low-resource settings to achieve zero central line-associated bloodstream infections.

## Key findings

- Implementation of insertion and maintenance bundles is emphasized for CLABSI prevention.
- A surveillance program is recommended to monitor compliance and outcomes.
- Additional measures are suggested for facilities with persistently high CLABSI rates.

## Abstract

To describe the revised Asia Pacific Society of Infection Control (APSIC) Guidelines for Prevention of Central Line Associated Blood Stream Infections (CLABSI) 2024.

The revised guidelines was developed by infection prevention and control experts and key opinion leaders from Asia Pacific.

Emphasis on practical implementation of Central Line Insertion and Maintenance Bundles using quality improvement approach is recommended towards the goal of achieving zero CLABSI in any healthcare setting.

Any patients with a central line in a healthcare setting

Literature search was done for recent international updates in CLABSI prevention. Recommendations were evaluated for practical and feasible implementation in low resourced settings.

The key recommendations are listed in the APSIC CLABSI insertion and maintenance guidelines. Additional measures are recommended for use where CLABSI rates remain high despite implementation of all preventive strategies to achieve institutional goals.

A surveillance program is recommended to monitor outcomes and compliance with bundles. Ongoing review of the performance data with appropriate interventions made should facilitate efforts towards zero CLABSI rate.

## Full-text entities

- **Diseases:** Central Line Associated Blood Stream Infections (MESH:D000086982), Infection (MESH:D007239), CLABSI (MESH:D018805)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12877909/full.md

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Source: https://tomesphere.com/paper/PMC12877909