# Relationship between adiponectin and insulin resistance among a cohort of obese adolescents and young adults in a tertiary institution

## TL;DR

This study found no significant link between adiponectin levels and insulin resistance in obese young people.

## Contribution

The study contributes new data on adiponectin and insulin resistance in a specific age group.

## Key findings

- Mean serum adiponectin level was 6.8 µg/ml.
- No significant correlation was found between adiponectin and insulin resistance markers.

## Abstract

To demonstrate the relationship between adiponectin and insulin resistance among adolescents and young adults

A cross-sectional descriptive study.

This study was conducted within a tertiary institution and the medical outpatient department (MOPD) of its adjourning tertiary health-care institution.

The study was conducted among students of a tertiary institution and patients attending the ABUAD Multi-system Hospital, aged 16-24 years.

The mean levels of serum adiponectin in obese adolescents and young adults and its relationship with clinical correlates of insulin resistance

Mean serum adiponectin level was 6.8 µg/ml, which is comparable to what has been obtained in other studies. Statistically non-significant negative correlations were noted between serum adiponectin and the homeostasis model assessment of insulin resistance (HOMA-IR), as well as with the clinical correlates of insulin resistance such as Body Mass Index and diastolic blood pressure.

This study demonstrated no significant correlation between serum adiponectin and markers of insulin resistance among these participants and may not be a useful marker of insulin resistance among this group of individuals; hence, its routine measurement may not be appropriate. A follow-up study involving more obese subjects may, however, be more revealing.

None declared