# Low-Load endoluminal navigation with a magnetically actuated medical soft microrobot

**Authors:** Julio Guerra, Andrei Malchikov, Sergey Jatsun, Petr Ryapolov, Andres Santiago Martinez-Leon

PMC · DOI: 10.3389/fmedt.2026.1717944 · Frontiers in Medical Technology · 2026-01-23

## TL;DR

This paper introduces a new control framework for a soft microrobot used in minimally invasive medical procedures, improving navigation accuracy and reducing forces on delicate tissues.

## Contribution

The novel contribution is a contact-aware control framework that optimizes magnet orientation to regulate force and improve microrobot navigation.

## Key findings

- Force-plus-angle control reduced tracking error and peak normal reaction force significantly compared to non-regulated operation.
- Monte Carlo analysis confirmed the robustness of the control framework under uncertainty and noise.
- Improved tracking does not inherently require higher contact forces, as shown in a trade-off analysis.

## Abstract

Minimally invasive endoluminal interventions increasingly rely on magnetic actuation to navigate narrow lumens while limiting wall loads. Here we present a contact-aware control framework for steering a deformable, silicone-based soft microrobot with embedded magnetic particles using an externally positioned permanent magnet. We develop a dynamic model capturing viscous drag, nonlinear frictional loads, and viscoelastic wall contact, and implement a closed-loop architecture that combines vision-based state estimation with model-based force inference while optimizing magnet orientation to regulate the force vector and normal reaction. Performance is evaluated in simulation and on a benchtop testbed across three control modes. In the nominal-case benchmark, force-plus-angle control reduced the root-mean-square tracking error from 4.8 to 2.1 mm (−56%), decreased peak tracking error from 14.6 to 8.0 mm (−45%), lowered the integrated performance index from 4.4 × 10−¹⁰ to 1.6 × 10−¹⁰ (−64%), and attenuated peak normal reaction force from 2.0 × 10−6 to 0.8 × 10−6
N (−60%) compared with operation without force regulation. To assess robustness, we further performed a simulation-based Monte Carlo analysis (n = 500 trials per mode) under parametric uncertainty and measurement noise, confirming that the contact-aware modes preserve their performance advantage; non-parametric tests indicated statistically significant inter-mode differences with moderate-to-large effect sizes. A trade-off analysis in the {tracking error, peak normal load} plane showed that, in the explored regime, improved tracking does not inherently require higher peak contact forces. Finally, a first-order shear-thinning surrogate suggested low sensitivity of the relative conclusions to moderate non-Newtonian effects. Overall, the results identify force-aware magnet orientation as a safety-relevant control degree of freedom for endoluminal navigation and provide a transferable control methodology for future magnetic microrobotic platforms.

## Full-text entities

- **Chemicals:** silicone (MESH:D012828)

## Full text

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## Figures

10 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12876258/full.md

## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12876258/full.md

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Source: https://tomesphere.com/paper/PMC12876258