# Pediatric-adult split liver transplantation: an ethical imperative and systems-based roadmap for global expansion

**Authors:** Tran Cong Duy Long, Huynh Tran Bao Chau, Dat Tien Le, Thi Tran Nguyen Minh, Bui Cong Minh, Anh Le Thien Diep, Hoang Bao Tran Van, Truc Thi Thu Huynh, Nguyen Tien Huy

PMC · DOI: 10.3389/frtra.2025.1709770 · Frontiers in Transplantation · 2026-01-23

## TL;DR

The paper argues for expanding split liver transplantation to better serve both children and adults in need of liver transplants.

## Contribution

The paper introduces a five-point action plan to scale up pediatric-adult split liver transplantation globally.

## Key findings

- Split liver transplantation is as effective as whole-liver transplants but is underused due to logistical and policy barriers.
- Centralized splitting hubs and new transport methods could help normalize split liver transplants.
- Global pilot programs are suggested to test and expand the adoption of split liver transplantation.

## Abstract

This paradox emphasizes the urgent need to re-engineer transplant systems around pediatric-adult split liver transplantation (SLT). Despite being as effective as whole-liver transplants, SLT remains underutilized due to logistical and policy barriers. We believe that expanding SLT is not only clinically acceptable but a just and effective moral necessity. We propose a five-point action plan, including centralized splitting hubs, NMP-enabled transport, and global pilot programs, to transform SLT from an exception into standard practice.

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12876239/full.md

## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12876239/full.md

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Source: https://tomesphere.com/paper/PMC12876239