# Radiation therapy for amyloid‐producing odontogenic tumor in a cat: a case report

**Authors:** A Uno, T Mori

PMC · DOI: 10.1111/avj.70021 · Australian Veterinary Journal · 2025-09-13

## TL;DR

A 10-year-old cat with a rare tumor in the mouth was successfully treated with radiation therapy when surgery wasn't possible.

## Contribution

This case report demonstrates the effectiveness of radiation therapy for treating a rare tumor in cats when surgery is not feasible.

## Key findings

- Radiation therapy achieved good tumor control with minimal side effects in a cat with APOT.
- The treatment protocol used a total dose of 42 Gy over six sessions.
- The cat showed favorable outcomes over a 481-day follow-up period.

## Abstract

Amyloid‐producing odontogenic tumor (APOT) is a rare odontogenic neoplasm in cats, characterized by amyloid deposition within the tumor. Surgical resection is commonly recommended, but in cases where complete excision is difficult, radiation therapy may be considered as an alternative treatment. In this case report, a 10‐year‐old male neutered domestic cat with an APOT of the maxilla was treated with radiation therapy and showed favorable outcomes. The treatment protocol involved a total dose of 42 Gy (Gray) administered over six sessions, with good tumor control, and minimal side effects observed over a 481‐day follow‐up period. This case suggests that radiation therapy can be an effective treatment option for APOT, particularly in cases where surgical excision is not feasible.

## Full-text entities

- **Diseases:** odontogenic neoplasm (MESH:D009369), amyloid (MESH:C000718787), APOT (MESH:D009808)
- **Species:** Felis catus (cat, species) [taxon 9685]

## Full text

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## Figures

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## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12875736/full.md

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Source: https://tomesphere.com/paper/PMC12875736