# Evaluation of morphological variations of mandibular bone in adult bruxers using CBCT: A cross-sectional study

**Authors:** Estelle Casazza, Benoit Ballester, Clémence Vernet, Camille Philip-Alliez, Anne Raskin, Cristiano Miranda de Araujo, Cristiano Miranda de Araujo, Sergio Luiz Mota-Junior, Sergio Luiz Mota-Junior, Sergio Luiz Mota-Junior

PMC · DOI: 10.1371/journal.pone.0342472 · PLOS One · 2026-02-05

## TL;DR

This study used CBCT scans to find that bruxers have higher mandibular bone density and lower mandibular angles compared to non-bruxers.

## Contribution

The study provides new empirical evidence on morphological differences in mandibular bone between bruxers and non-bruxers using CBCT analysis.

## Key findings

- Bruxers showed significantly higher bone density in specific mandibular regions compared to non-bruxers.
- Mandibular angle values were significantly lower in bruxers than in non-bruxers.
- The study identified morphological differences in mandibular bone structure between bruxers and non-bruxers.

## Abstract

This cross-sectional study aimed to establish whether a difference exists between the mandibular bone density and the mandibular angle values of adult bruxer and non-bruxer patients, based on a CBCT analysis. CBCT scans of bruxer and non-bruxer patients were analysed with two software packages, 3D Slicer® and Romexis®. Bone density in the alveolar bone below and immediately adjacent to the apices of teeth 31, 33, 34, 41, 43, 44, and the mesial apices of teeth 36 and 46, was recorded in Hounsfield units with 3D Slicer®. The mandibular angle between the corpus and ramus tangent lines was measured using Romexis® software. 113 CBCT scans were included in the study of alveolar bone density, of which 78 were used to study mandibular angle values. A statistically significant difference (p < 0.05) was noted between the density values of the two groups, with higher values in bruxers than in non-bruxers. Mandibular angle values were significantly lower in bruxers (p < 0.05). This cross-sectional study based on CBCT imaging showed certain morphological differences between the mandibles of bruxers and those of non-bruxers. Further studies are needed to supplement this preliminary research, in particular prospective studies.

## Full-text entities

- **Genes:** PTH (parathyroid hormone) [NCBI Gene 5741] {aka FIH1, PTH1}
- **Diseases:** tooth wear (MESH:D057085), hormone deficiency (MESH:D004393), mandibular fracture (MESH:D008337), maxillary edentulism (MESH:D008439), bone metastases (MESH:D009362), fracture (MESH:D050723), root resorption (MESH:D012391), periapical inflammation (MESH:D007249), masseter hypertrophy (MESH:C563600), bone necrosis (MESH:D010020), myalgia (MESH:D063806), remodelling (MESH:D020257), fatigue fracture (MESH:D015775), mandibular asymmetry (MESH:D008338), caries (MESH:D003731), osteoporosis (MESH:D010024), hyperactivity of the elevator (MESH:D006948), tooth loss (MESH:D016388), alveolar bone exostosis (MESH:D016301), Bruxism (MESH:D002012)
- **Chemicals:** water (MESH:D014867), CASAZZA (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12875488/full.md

## References

38 references — full list in the complete paper: https://tomesphere.com/paper/PMC12875488/full.md

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Source: https://tomesphere.com/paper/PMC12875488