# Prognostic accuracy of the CMPMIT-ICD-10, APACHE Ⅱ, SOFA, ISS, and AIS for in-hospital death among patients with traumatic hemorrhagic shock

**Authors:** Jie Cai, Gang Zhou, Feifei Jin, Haiyan Xue, Shu Li, Chun Fu, Zhenzhou Wang, Wei Huang, Tianbing Wang, Fengxue Zhu, Xiujuan Zhao, Alaa Oteir, Alaa Oteir, Alaa Oteir

PMC · DOI: 10.1371/journal.pone.0340159 · PLOS One · 2026-02-05

## TL;DR

A new trauma scoring system called CMPMIT-ICD-10 was found to be more accurate than existing systems in predicting in-hospital death for patients with traumatic hemorrhagic shock.

## Contribution

The CMPMIT-ICD-10 trauma scoring system is introduced and shown to outperform established models like APACHE II, SOFA, ISS, and AIS in predicting mortality in traumatic hemorrhagic shock patients.

## Key findings

- CMPMIT-ICD-10 had the highest AUC (0.8757) for predicting in-hospital death among traumatic hemorrhagic shock patients.
- CMPMIT-ICD-10 showed high sensitivity (85.4%) and specificity (79.9%) at a cut-off value of 59.5.
- CMPMIT-ICD-10 was independently associated with in-hospital death (OR 1.057, p < 0.001).

## Abstract

The China Mortality Prediction Model in Trauma, which is based on the International Classification of Disease Disorders (ICD)-10-CM lexicon (CMPMIT-ICD-10),is a new trauma scoring system. Our objective was to compare the prognostic performance of the CMPMIT-ICD10 with that of the Acute Physiology and Chronic Health Evaluation II (APACHEII), Sequential Organ Failure Assessment (SOFA), Injury Severity Score (ISS), and Abbreviated Injury Scale (AIS) for in-hospital mortality in patients with traumatic hemorrhagic shock(THS).This retrospective observational cohort study was conducted at a tertiary teaching hospital from May 1, 2013, to May 31, 2023.The area under the receiver operating characteristic curve (AUC), sensitivity, specificity, accuracy, and associations with outcomes of theCMPMIT-ICD-10, APACHE II, SOFA, ISS, and AIS scores for the prediction of in-hospital death were assessed. A total of 420 patients with THS were included. Forty-one (9.8%) patients died during hospitalization. For the prediction of in-hospital death, the CMPMIT-ICD-10 (0.8757) and APACHE II(0.8709) had greater AUCs compared with the AIS (0.6243), SOFA (0.7669), and ISS (0.6601). With the best cut-off value of 59.5, the CMPMIT-ICD10 had a highest sensitivity (85.4%) and good specificity(79.9%) and overall accuracy (80.4%). The CMPMIT-ICD10 (OR 1.057, 95% CI 1.028–1.087, p < 0.001) and APACHE II (OR 1.125, 95% CI 1.045–1.211, p = 0.002) were independently associated with in-hospital death. Comparable to the APACHE II but significantly better than the SOFA, ISS, and AIS, the CMPMIT-ICD-10 performed well in predicting the short-term mortality of patients with THS. These findings suggest that the CMPMIT-ICD-10 may have superior utility for predicting short-term death in THS patients.

## Full-text entities

- **Genes:** TNNI3 (troponin I3, cardiac type) [NCBI Gene 7137] {aka CMD1FF, CMD2A, CMH7, RCM1, TNNC1, cTnI}, F2 (coagulation factor II, thrombin) [NCBI Gene 2147] {aka PT, RPRGL2, THPH1}, GPT (glutamic--pyruvic transaminase) [NCBI Gene 2875] {aka AAT1, ALT, ALT1, GPT1, SGPT}
- **Diseases:** Failure (MESH:D051437), blood loss (MESH:D016063), THS (MESH:D012771), Acute kidney injury (MESH:D058186), APACHEII (MESH:D000071069), bleeding (MESH:D006470), liver cirrhosis (MESH:D008103), critical illness (MESH:D016638), coagulopathy (MESH:D001778), Multiple Organ Dysfunction Syndrome (MESH:D009102), ORCID iD (MESH:C535742), Injury (MESH:D014947), Death (MESH:D003643), dying (MESH:D064806), Disease (MESH:D004194), acute or chronic hepatitis (MESH:D065290), Acute liver injury (MESH:D017114), AIS (MESH:C538175), ISS (MESH:D045169), shock (MESH:D012769), Acute Physiology (MESH:D000208), Myocardial injury (MESH:D009202), multiple injuries (MESH:D009104), Acute respiratory distress syndrome (MESH:D012128), blunt trauma (MESH:D014949), traumatic shock (MESH:D012774)
- **Chemicals:** lactate (MESH:D019344), creatinine (MESH:D003404), PONE-D-24-58143R1 (-), bilirubin (MESH:D001663), oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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## References

44 references — full list in the complete paper: https://tomesphere.com/paper/PMC12875474/full.md

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Source: https://tomesphere.com/paper/PMC12875474