# Correction: Nicotine promotes brain metastasis by polarizing microglia and suppressing innate immune function

**Authors:** Shih-Ying Wu, Fei Xing, Sambad Sharma, Kerui Wu, Abhishek Tyagi, Yin Liu, Dan Zhao, Ravindra Pramod Deshpande, Yusuke Shiozawa, Tamjeed Ahmed, Wei Zhang, Michael Chan, Jimmy Ruiz, Thomas W. Lycan, Andrew Dothard, Kounosuke Watabe

PMC · DOI: 10.1084/jem.2019113101262026c · The Journal of Experimental Medicine · 2026-02-05

## Full-text entities

- **Genes:** Iba1 (induction of brown adipocytes 1) [NCBI Gene 114737], Stat3 (signal transducer and activator of transcription 3) [NCBI Gene 20848] {aka 1110034C02Rik, Aprf}, Mrc1 (mannose receptor, C type 1) [NCBI Gene 17533] {aka CD206, MR}, Ccl20 (C-C motif chemokine ligand 20) [NCBI Gene 20297] {aka CKb4, LARC, MIP-3A, MIP-3[a], MIP3A, ST38}, Ptprc (protein tyrosine phosphatase receptor type C) [NCBI Gene 19264] {aka B220, CD45R, Cd45, L-CA, Ly-5, Lyt-4}, Jak2 (Janus kinase 2) [NCBI Gene 16452] {aka Fd17}, Arg1 (arginase, liver) [NCBI Gene 11846] {aka AI, Arg-1, PGIF}, Itgam (integrin alpha M) [NCBI Gene 16409] {aka CD11b/CD18, CR3, CR3A, Cd11b, F730045J24Rik, Ly-40}
- **Diseases:** Metastatic brain tumors (MESH:D001932), lung cancer (MESH:D008175), tumor (MESH:D009369), brain metastasis (MESH:D009362), Metastatic (MESH:D000092182)
- **Chemicals:** PKH26 (MESH:C070080), PLX3397 (MESH:C000600259), DMEM (-), Nicotine (MESH:D009538), PBS (MESH:D007854)
- **Species:** Mus musculus (house mouse, species) [taxon 10090], Homo sapiens (human, species) [taxon 9606]
- **Cell lines:** S2 — Drosophila melanogaster (Fruit fly), Spontaneously immortalized cell line (CVCL_Z232), THP-1 — Homo sapiens (Human), Childhood acute monocytic leukemia, Cancer cell line (CVCL_0006), LL/2 — Mus musculus (Mouse), Hybridoma (CVCL_C4DW), HMC3 — Homo sapiens (Human), Transformed cell line (CVCL_II76), C57BL/6 — Mus musculus (Mouse), Transformed cell line (CVCL_C0MU), H2030BrM — Homo sapiens (Human), Lung adenocarcinoma, Cancer cell line (CVCL_XA22)

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Source: https://tomesphere.com/paper/PMC12875310