# Two-Day Mohs Excision of Large Scalp Dermatofibrosarcoma Protuberans Reconstructed With a Rotation Flap

**Authors:** Jeison De Guzman, Zaineb Makhzoumi, Ronald P Silverman

PMC · DOI: 10.7759/cureus.100911 · Cureus · 2026-01-06

## TL;DR

A large scalp tumor was successfully removed in two days using Mohs surgery and reconstructed with a flap and skin graft.

## Contribution

Demonstrates successful two-day Mohs excision and reconstruction for a large scalp DFSP under local anesthesia.

## Key findings

- A 10x10 cm DFSP was completely excised using staged Mohs surgery over two days.
- Reconstruction with a rotation flap and skin graft achieved successful closure despite extensive tissue loss.
- The case shows that large scalp DFSP can be treated effectively with MMS under local anesthesia.

## Abstract

Dermatofibrosarcoma protuberans (DFSP) is a rare, slow-growing, locally aggressive, cutaneous sarcoma with a high recurrence risk. Mohs micrographic surgery (MMS) offers superior margin control but presents significant reconstructive challenges in large scalp lesions. We present a 36-year-old male with a large (10 x 10 cm) DFSP of the frontal scalp requiring staged two-day MMS for complete clearance. Despite an extensive defect down to the periosteum and partial calvarium exposure, closure was achieved with a large rotational advancement flap with a split-thickness skin graft. This case highlights that even exceptionally large scalp DFSP lesions can be successfully excised under local anesthesia with MMS.

## Linked entities

- **Diseases:** Dermatofibrosarcoma protuberans (MONDO:0011934), DFSP (MONDO:0011934)

## Full-text entities

- **Diseases:** scalp lesions (MESH:D004476), DFSP (MESH:D018223), cutaneous sarcoma (MESH:D012509)

## Full text

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## Figures

12 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12874930/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12874930/full.md

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Source: https://tomesphere.com/paper/PMC12874930