# A brief review of chikungunya fever: From molecular virology to countermeasures

**Authors:** Xin Zhang, Xiaoxi Li, Tianjun Jiang, Junliang Fu

PMC · DOI: 10.1016/j.imj.2025.100231 · 2025-12-25

## TL;DR

This paper reviews chikungunya fever, covering its causes, symptoms, diagnosis, and treatment, and suggests future research directions.

## Contribution

The paper integrates findings from various studies to propose new research and intervention strategies for chikungunya fever.

## Key findings

- Chikungunya fever is a growing global health concern due to its increasing spread and severity.
- Current research highlights gaps in vaccine development and treatment strategies for CHIKF.
- Future directions include improved diagnostics and targeted therapies based on molecular virology insights.

## Abstract

Chikungunya fever (CHIKF), resulting from the chikungunya virus infection, has become a major global health issue in recent years. This review summarizes the epidemiology, virology, pathogenesis, clinical manifestations, diagnosis, vaccine development and treatment strategies of the CHIKF. And by integrating the findings from various studies, an attempt is made to propose future research directions and intervention strategies.

Image, graphical abstract

## Linked entities

- **Diseases:** chikungunya fever (MONDO:0017941)

## Full-text entities

- **Diseases:** CHIKF (MESH:D065632)

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12874598/full.md

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Source: https://tomesphere.com/paper/PMC12874598