# Primary Peritoneal Carcinomatosis: A Case Report

**Authors:** Anvitha Soundararajan, Rodrigo Furlan Silva Fabri, Barney Soskin

PMC · DOI: 10.7759/cureus.100774 · 2026-01-04

## TL;DR

This paper presents a case of primary peritoneal cancer, a rare disease that looks similar to ovarian cancer and is hard to diagnose without an ovarian mass.

## Contribution

The paper highlights the diagnostic challenges of primary peritoneal adenocarcinoma and emphasizes its clinical significance for prognosis and management.

## Key findings

- Primary peritoneal adenocarcinoma shares similarities with ovarian cancer but lacks detectable ovarian masses.
- Accurate diagnosis of PPC is crucial for proper genetic counseling and treatment planning.

## Abstract

Primary peritoneal adenocarcinoma (PPC) is an uncommon malignancy that arises from the peritoneal lining and shares striking clinical, histopathological, and immunophenotypic similarities with epithelial ovarian carcinoma (EOC). Because both entities derive from Müllerian epithelium, distinguishing PPC from metastatic ovarian or gastrointestinal carcinoma poses a significant diagnostic challenge, particularly in the absence of detectable ovarian masses. Recognizing this rare entity is clinically relevant, as accurate classification influences prognosis, genetic counseling, and management strategies.

## Full-text entities

- **Diseases:** EOC (MESH:D000077216), ovarian masses (MESH:D010049), Primary Peritoneal Carcinomatosis (MESH:D010534), ovarian or gastrointestinal carcinoma (MESH:D010051), malignancy (MESH:D009369), PPC (MESH:D010538)

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12874186/full.md

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Source: https://tomesphere.com/paper/PMC12874186