Primary Cardiac Lymphoma With Exceptional Long-Term Survival

TL;DR

A 53-year-old man with primary cardiac lymphoma achieved long-term remission after surgery and chemoimmunotherapy, showing the disease can be effectively treated.

Contribution

This case report demonstrates exceptional long-term survival in primary cardiac lymphoma with timely and appropriate treatment.

Findings

The patient remained disease-free 128 months after treatment.

Surgical excision and R-CHOP chemoimmunotherapy led to sustained complete metabolic remission.

Accurate diagnosis and therapy are critical for prolonged survival in PCL.

Abstract

Primary cardiac lymphoma (PCL) is an uncommon extranodal lymphoma confined to the heart or pericardium at diagnosis and can mimic other cardiac disorders because of its nonspecific presentation. We report a 53-year-old man diagnosed in 2015 with diffuse large B-cell lymphoma involving the right atrium. He underwent surgical excision followed by six cycles of R-CHOP chemoimmunotherapy. Serial PET/CT and echocardiography confirmed sustained complete metabolic remission, and he remains disease-free 128 months after treatment. This case highlights the potential for prolonged survival in PCL when timely diagnosis, accurate histopathological confirmation, and appropriate therapy are provided.

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