# A 1.5-year randomized controlled trial comparing standard-sized implants and two diameters of mini-implants immediately loaded by mandibular overdenture: radiographic outcomes, short-term survival, and success rate

**Authors:** Heba M. Moftah, Mohannad H. Al-Saadi, Khaldoun Darwich

PMC · DOI: 10.1038/s41405-025-00369-x · 2026-02-04

## TL;DR

This study compared standard and mini dental implants loaded immediately with dentures, finding that smaller implants had slightly worse bone loss but all had high survival rates.

## Contribution

The study provides new radiographic and success rate data for mini-implants of different diameters under immediate loading.

## Key findings

- Standard implants showed better radiographic outcomes and success rates than mini-implants.
- All groups had a 100% survival rate after 18 months of loading.
- Smaller implant diameters correlated with increased marginal bone level changes.

## Abstract

This study aims to evaluate the marginal bone level changes (MBLC), survival, and success rate of 4 mini-implants (MIs) of two different diameters versus two standard-sized implants (SIs) that were loaded functionally and immediately by a complete mandibular denture.

The study comprised 29 participants with conventional complete dentures; they were randomly allocated into three groups. Group S included 11 participants who received two SIs of 3.75 mm diameter, group M3 included 8 participants who received four MIs of 3 mm diameter, and group M2.5 included 10 participants who received four MIs of 2.5 mm diameter. MBLC was evaluated on each implant’s mesial and distal sides after 18 months of loading. A paired t-test and one-way ANOVA were used for intragroup and intergroup comparisons, respectively (P ≤ 0.05). The evaluation of survival and success rates adhered to the criteria established by the International Congress of Oral Implantologists in Pisa (2007).

Immediate loading was employed in all cases. No failure occurred in any case. The success rate after 18 months was 90.91% in the S group, 90.63% in the M3 group, and 90% in the M2.5 group. MBLC after 18 months of loading were 0.76 ± 0.62 mm mesially and 0.63 ± 0.90 mm distally in the S group, 1.04 ± 0.72 mm mesially and 1.05 ± 0.84 mm distally in the M3 group, and 1.37 ± 0.73 mm mesially and 1.11 ± 0.68 mm distally in the M2.5 group.

The SIs group showed better radiographic results and success rates than the MIs groups. As the diameter of the implant decreases, the mean MBLC increases. However, the results of the MIs groups were within acceptable limits. The survival rate was 100% in the three groups.

## Full-text entities

- **Diseases:** fracture (MESH:D050723), tenderness (MESH:D063806), gingival overgrowth (MESH:D019214), SIs (MESH:D015875), osteoporosis (MESH:D010024), disorder of calcium ion metabolism (MESH:D002128), muscle atrophy (MESH:D009133), postoperative pain (MESH:D010149), edentulism (MESH:D007575), bone resorption (MESH:D001862), pain (MESH:D010146), uncontrolled diabetes (MESH:D003920), necrosis (MESH:D009336), mandibular overdentures (MESH:D008338), bone necrosis (MESH:D010020), COVID (MESH:D000086382), MBLC (MESH:D001847), MIs (MESH:D057873), resorption (MESH:D014091), disorders of the temporomandibular joint (MESH:D013705)
- **Chemicals:** povidone (MESH:D011205), dexamethasone (MESH:D003907), steroids (MESH:D013256), chlorhexidine (MESH:D002710), acrylic (-), diclofenac sodium (MESH:D004008), adrenaline (MESH:D004837), bisphosphonates (MESH:D004164), lidocaine (MESH:D008012)
- **Species:** Canis lupus familiaris (dog, subspecies) [taxon 9615], Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12873324/full.md

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Source: https://tomesphere.com/paper/PMC12873324