# Dataset of Oddball Paradigm experiment in the Auditory Cortex and the effect of acetylcholine

## TL;DR

This paper provides open datasets of rat auditory cortex neural recordings to study how the brain processes unexpected sounds and the role of acetylcholine.

## Contribution

The novelty lies in providing open datasets with neural recordings from the auditory cortex during an oddball paradigm and acetylcholine application.

## Key findings

- Neural recordings show responses to standard and deviant tones in rat auditory cortex.
- The datasets allow investigation of cholinergic modulation and predictive-coding mechanisms.
- Data capture stimulus-specific adaptation and deviance detection at multiple temporal scales.

## Abstract

This work presents three open datasets featuring various levels of processing, containing neural recordings from the auditory cortex of rats. These recordings were obtained during experiments using the auditory oddball paradigm before, during and after the local microiontophoretic application of acetylcholine. The primary objective of these datasets is to investigate how the brain processes predictable versus unexpected auditory stimuli, and the role of cholinergic inputs during such processing. The data include multi-unit recordings of neuronal activity during the presentation of standard and deviant tones, classified by stimulus type and cortical sub-region. These resources enable quantitative investigations of deviance detection, stimulus-specific adaptation, cholinergic modulation and predictive-coding mechanisms at multiple temporal scales.