# Case Report: Prenatal presentation of Masson's tumor: first reported case and review of the literature

**Authors:** Bahattin Tanrıkulu, Ayça Erşen Danyeli, M. Memet Özek

PMC · DOI: 10.3389/fped.2026.1636879 · 2026-01-22

## TL;DR

This paper reports the first prenatal case of a rare benign brain tumor called Masson's tumor in a fetus, emphasizing early detection for better management.

## Contribution

The study presents the first prenatal diagnosis of intravascular papillary endothelial hyperplasia (IPEH) in a fetal intracranial mass.

## Key findings

- A prenatal case of intravascular papillary endothelial hyperplasia (IPEH) was diagnosed at 34 weeks gestation.
- This is the first reported prenatal presentation of IPEH, previously only diagnosed in adults and rarely in children.
- Early prenatal detection can improve perinatal and surgical management of such rare vascular lesions.

## Abstract

Intravascular papillary endothelial hyperplasia (IPEH), or Masson's tumor, is a rare, benign vascular lesion that can closely resemble malignant vascular tumors. While primarily diagnosed in adulthood, pediatric cases are uncommon, and no prenatal diagnoses have been reported to date. Here, we present the first documented prenatal presentation of fetal intracranial IPEH detected in utero at 34 weeks of gestation. This case highlights the importance of considering IPEH in the differential diagnosis of fetal intracranial masses and underscores the role of early prenatal detection in optimizing perinatal and surgical management.

## Linked entities

- **Diseases:** intravascular papillary endothelial hyperplasia (MONDO:0043349), Masson's tumor (MONDO:0043349)

## Full-text entities

- **Diseases:** IPEH (MESH:D002291), malignant vascular tumors (MESH:D018198), Masson's tumor (MESH:D009369), fetal intracranial masses (MESH:D005315), vascular lesion (MESH:D014652)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12872910/full.md

---
Source: https://tomesphere.com/paper/PMC12872910