# The Jaga Diri digital intervention improved knowledge and adherence to weekly iron-folic acid supplementation among adolescent girls in Maluku Province, Indonesia

**Authors:** Lershito Antonio Pasamba, Christiana Rialine Titaley, Sean Samuel Istia, Ritha Tahitu, Elpira Asmin, Farah Christina Noya, Mega Clarita Laurence, Yudhie Djuhastidar Tando, Maxwell Landri Vers Malakauseya, Liyani Sartika Sara

PMC · DOI: 10.3389/fdgth.2025.1729623 · 2026-01-22

## TL;DR

A digital app called Jaga Diri improved knowledge and adherence to iron-folic acid supplements in adolescent girls in Indonesia, reducing anemia rates.

## Contribution

The Jaga Diri app is a novel digital intervention that effectively improves adherence to IFA supplementation in adolescent girls.

## Key findings

- Adolescent girls using the Jaga Diri app showed significantly higher knowledge about anemia.
- Adherence to IFA supplementation improved, reducing anemia prevalence from 35% to 17.5% in the intervention group.
- The control group saw an increase in anemia prevalence from 19% to 28.6%.

## Abstract

Adherence to weekly iron/folic acid (IFA) supplementation, a vital intervention to combat anaemia among adolescent girls, remains a global challenge, including in Maluku Province, Indonesia. This study assessed the effect of “Jaga Diri” application, in enhancing knowledge and adherence to IFA supplementation among adolescent girls from Salahutu Sub-District of Maluku Province, Indonesia.

In mid-2024, a quasi-experimental study was conducted among 82 adolescent girls from two senior high schools in Salahutu Sub-District, Maluku Province, Indonesia. The intervention group used the “Jaga Diri” Android-based application for four weeks, which delivered weekly reminders and brief educational messages on anaemia and iron–folic acid (IFA) supplementation, while the control group received routine school-based services. Knowledge was measured using a validated 15-item questionnaire. Adherence was defined as consumption of ≥75% of the provided weekly IFA tablets over the previous four weeks, assessed by self-report, and supported by haemoglobin measurement. Group differences were analyzed using non-parametric and chi-square tests, and multivariable binary logistic regression was used to assess factors associated with high knowledge and adherence.

After four weeks of using the “Jaga Diri” application, adolescent girls from the intervention school showed a significantly higher level of knowledge about anaemia (p = 0.011) and adherence to weekly IFA supplementation (p < 0.001) than those from the control school. The improved adherence was shown by the reduction of anaemia prevalence in the intervention school, from 35% to 17.5%. In the control school, the prevalence increased from 19% to 28.6%.

The “Jaga Diri” application effectively improves knowledge about anaemia and adherence to IFA supplementation among adolescent girls. Further investigation with larger and more varied groups are required to confirm its effectiveness before it can be widely implemented in larger areas of Maluku and Indonesia.

## Full-text entities

- **Diseases:** anaemia (MESH:D000743)
- **Chemicals:** IFA (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12872849/full.md

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Source: https://tomesphere.com/paper/PMC12872849