# Computational Predictive Modeling of Surgical Outcomes in Total Anomalous Pulmonary Venous Connection: Assessing the Impact of Pulmonary Venous Confluence Size on Preoperative Planning

## TL;DR

This paper presents a computational model to predict optimal anastomosis sizing in TAPVC surgery, emphasizing the importance of pulmonary venous confluence size for accurate preoperative planning.

## Contribution

The study introduces a patient-specific fluid–structure interaction model that incorporates pulmonary venous confluence size to improve surgical outcome predictions.

## Key findings

- A strong positive correlation was found between flow velocity and the ratio of body weight to anastomosis length and PVC circumference.
- Including PVC size in the model significantly improved predictive accuracy.
- Predicted and measured flow velocities showed no significant difference.

## Abstract

To develop a predictive model for optimal anastomosis sizing in TAPVC surgery, focusing on the role of pulmonary venous confluence (PVC) size. A patient-specific fluid–structure interaction (FSI) model simulated blood flow through various anastomosis sizes. Key variables included body weight, anastomosis length, and PVC size. The model's predictions were validated against postoperative echocardiographic measurements from nine TAPVC cases. A strong positive correlation was found between flow velocity and the ratio of body weight to anastomosis length and PVC circumference. Including PVC size significantly improved predictive accuracy. No significant difference was observed between predicted and measured velocities. PVC size is a critical factor for planning TAPVC surgery. Incorporating it into computational models enhances the prediction of flow dynamics and supports personalized surgical decision-making.

The online version contains supplementary material available at 10.1007/s12265-025-10725-9.