Zea mays–Derived Zinc Oxide Nanoparticles Exhibiting Enhanced Antioxidant, Antibacterial, and Wound‐Healing Activities
Aqsa Khalid, Raheela Waheed, Zermina Rashid, Farah Deeba, Ambreen Aleem, Mohamed Deifallah Yousif
TL;DR
This paper explores the use of corn-derived zinc oxide nanoparticles for wound healing and antibacterial purposes.
Contribution
The study introduces a green synthesis method for zinc oxide nanoparticles using Zea mays leaf extract and evaluates their wound-healing and antibacterial properties.
Findings
ZnZM NPs showed significant antibacterial activity against E. coli, P. aeruginosa, and K. pneumoniae.
Topical gels with ZnZM NPs accelerated wound healing in rats compared to controls.
The nanoparticles exhibited strong antioxidant properties, including ferric ion-reducing power and free radical-scavenging ability.
Abstract
Infections are a cause of delayed wound healing, and the development of effective therapeutic strategies remains a key challenge. This study is aimed at developing and evaluating Zea mays leaf extract‐mediated zinc oxide nanoparticles (ZnZM NPs) for their antibacterial, antioxidant, and wound‐healing potential. Z. mays leaf extract was utilized for the green synthesis of ZnZM NPs, which were characterized using multiple analytical techniques. The UV‐visible spectrum exhibited a characteristic sharp absorption peak at 390 nm, and energy‐dispersive X‐ray (EDX) spectrometry confirmed the presence of zinc and oxygen. FT‐IR confirmed that the phytochemicals from Z. mays extract were involved in the reduction and capping of NPs. The ZnZM NPs were slightly aggregated, partially spherical, and crystalline, with an average crystallite size of 10.86 nm. The nanoparticles exhibited significant…
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Taxonomy
TopicsWound Healing and Treatments · Nanoparticles: synthesis and applications · Nanocomposite Films for Food Packaging