# Clinical outcomes after mix-and-match implantation of monofocal and refractive multifocal intraocular lenses after surgery

**Authors:** Ying Xing, Fuqiang Li, Yaru Wang, Zengfei Ma, Zengjie Wang, Hui Zhang

PMC · DOI: 10.3389/fmed.2025.1579025 · 2026-01-22

## TL;DR

Mixing monofocal and multifocal lenses in cataract surgery improves vision quality and reduces reliance on glasses.

## Contribution

Demonstrates hybrid monovision's effectiveness in binocular cataract treatment.

## Key findings

- Mixed implantation improved intermediate and near visual acuity significantly.
- Patients with mixed lenses reported better visual function and stereoscopic vision.
- Hybrid monovision achieved higher spectacle independence rates.

## Abstract

To analyze the visual acuity, visual quality, and stereoscopic function of patients with binocular cataracts following mixed refractive multifocal intraocular lens (MIOL) (Lentis Comfort LS-313 MF15; Oculentis GmbH, Germany) and monofocal IOL (Tecnis ZCB00; Johnson & Johnson Vision, USA) implantation.

The study was conducted at the Eye Center of our hospital between January 2023 and December 2023.

This was a retrospective, case–control study.

This retrospective study compared mixed implantation (LS-313 MF15 in non-dominant eye + ZCB00 in dominant eye, n = 30) versus bilateral monofocal implantation (ZCB00, n = 30). Visual acuity (uncorrected distance visual acuity (UDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA)), defocus curves, stereopsis, and patient-reported outcomes were assessed at 3 months.

Sixty patients (120 eyes) were enrolled. Group A exhibited significantly better UIVA (p < 0.001) and UNVA (p < 0.001) than Group B. The defocus curve indicated more continuous visual acuity in Group A, which had a significantly better postoperative VF-14 (Visual Function Index-14) score (p < 0.001) and spectacle independence rate than Group B. Near-stereoscopic acuity measured using Titmus card showed clearer stereoscopic vision in Group A than in Group B, with a significant difference (p < 0.001).

Hybrid monovision may be an effective approach for patients with binocular cataracts since the concept of partial monovision is well-suited for the desire of eyeglass independence.

## Full-text entities

- **Diseases:** cataracts (MESH:D002386)
- **Chemicals:** MF15 (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12872502/full.md

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Source: https://tomesphere.com/paper/PMC12872502