Cortisol–CRP synchrony and mood recovery under clustered psychosocial stress in emerging adults
Fatin Nabila Abd Latiff, Dawn A. Stoner, Kah Lun Wang, Kok Bin Wong
TL;DR
This study explores how clustered psychosocial stress affects cortisol and CRP synchrony, influencing mood recovery in young adults.
Contribution
The study introduces a novel bi-axial pathway linking clustered stress to psychological outcomes through cortisol–CRP coordination.
Findings
Higher cumulative stress units disrupt cortisol–CRP synchrony and delay mood recovery.
Stronger physiological coupling between cortisol and CRP predicts faster emotional recovery.
Clustered stressors show a stronger impact on emotional resilience than isolated stressors.
Abstract
Psychosocial stress involving multiple life changes has well-documented effects on health, yet the physiological mechanisms linking stress exposure to emotional recovery remain incompletely understood. This simulation study examines how clustered life stress, quantified through the Holmes and Rahe Social Readjustment Rating Scale (SRRS) and Life Change Units (LCUs), influences synchrony between cortisol and C-reactive protein (CRP), and how this coupling predicts mood recovery in emerging adults. Using fully synthetic longitudinal data parameterized from published empirical ranges and established biometric patterns, we modeled cortisol–CRP coordination across varying LCU loads and buffering capacities. Results indicated that higher cumulative LCUs, particularly when stressors were temporally clustered, were associated with disrupted cortisol–CRP synchrony and delayed mood rebound.…
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Taxonomy
TopicsStress Responses and Cortisol · Mental Health Research Topics · Evolutionary Psychology and Human Behavior