# Shaking Up the Synthesis of Organophosphorus Compounds via Ortho-phosphite

**Authors:** Alexandros Paparakis, Andrew R. Jupp

PMC · DOI: 10.1021/acscentsci.5c02384 · 2026-01-06

## TL;DR

This paper presents a new mechanochemical method to synthesize ortho-phosphite, a key organophosphorus compound.

## Contribution

A novel mechanochemical route to produce the [PO3]3− anion from condensed phosphates is introduced.

## Key findings

- Mechanochemistry successfully generates the ortho-phosphite anion from condensed phosphates.
- The method avoids traditional solution-based approaches, offering a more sustainable synthesis route.

## Abstract

Mechanochemistry
enables the preparation of the fundamental ortho-phosphite [PO3]3− anion from condensed phosphates.

## Linked entities

- **Chemicals:** [PO3]3− (PubChem CID 107908)

## Full-text entities

- **Chemicals:** Organophosphorus Compounds (MESH:D009943), Ortho-phosphite (-), phosphates (MESH:D010710)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12871879/full.md

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Source: https://tomesphere.com/paper/PMC12871879