# Bilateral Adrenal Hemorrhage After Laminectomy: A Rare Complication

**Authors:** Sapna Sharma, Michelle Ashley Rizk, Hafiza Qadeer, Rubina Paudel, Chheki Sherpa

PMC · DOI: 10.1210/jcemcr/luaf328 · 2026-02-04

## TL;DR

A 63-year-old man developed a rare and life-threatening adrenal hemorrhage after back surgery, which was successfully treated with steroids.

## Contribution

This case report highlights bilateral adrenal hemorrhage as a rare postoperative complication that should be considered in patients with nonspecific symptoms.

## Key findings

- The patient developed bilateral adrenal hemorrhage following laminectomy and exhibited adrenal insufficiency symptoms.
- Intravenous hydrocortisone treatment led to rapid clinical improvement in the patient.
- The case emphasizes the importance of considering adrenal hemorrhage in postoperative patients with hemodynamic instability.

## Abstract

Bilateral adrenal hemorrhage is a rare but life-threatening condition that can result in adrenal insufficiency. We present the case of a 63-year-old man who developed bilateral adrenal hemorrhage following a fall from 3 feet height on a ladder. He fell backwards, striking his lower back on the adjacent dry wall and landed on the ground. He was admitted for a traumatic L1 burst fracture and was treated with T11-L3 fusion and T12-L3 laminectomy. Postoperatively, he received prophylactic subcutaneous unfractionated heparin and later developed unexplained tachycardia, pulmonary embolism, and bilateral adrenal masses. He was subsequently readmitted with altered mental status, hypotension, and profound electrolyte abnormalities. Laboratory evaluation revealed undetectable cortisol and elevated adrenocorticotropic hormone (ACTH), consistent with primary adrenal insufficiency. Imaging confirmed hyperdense bilateral adrenal masses. Infectious causes were excluded, and heparin-induced thrombocytopenia was ruled out. The patient was treated with intravenous hydrocortisone, leading to rapid clinical improvement. He was discharged on oral steroid therapy and remains well on follow-up. This case highlights the importance of considering bilateral adrenal hemorrhage in postoperative patients presenting with nonspecific symptoms and hemodynamic instability.

## Linked entities

- **Chemicals:** hydrocortisone (PubChem CID 5754)
- **Diseases:** adrenal insufficiency (MONDO:0000004), bilateral adrenal hemorrhage (MONDO:0017871), pulmonary embolism (MONDO:0005279)

## Full-text entities

- **Genes:** POMC (proopiomelanocortin) [NCBI Gene 5443] {aka ACTH, CLIP, LPH, MSH, NPP, OBAIRH}
- **Diseases:** electrolyte abnormalities (MESH:D014883), pulmonary embolism (MESH:D011655), burst fracture (MESH:C562695), Infectious (MESH:D003141), Bilateral Adrenal Hemorrhage (MESH:D014884), primary adrenal insufficiency (MESH:D000224), adrenal masses (MESH:C536030), hypotension (MESH:D007022), tachycardia (MESH:D013610), thrombocytopenia (MESH:D013921), adrenal insufficiency (MESH:D000309)
- **Chemicals:** steroid (MESH:D013256), cortisol (MESH:D006854), heparin (MESH:D006493)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12871072/full.md

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Source: https://tomesphere.com/paper/PMC12871072