# Missing Value Imputation With Adversarial Random Forests—MissARF

**Authors:** Pegah Golchian, Jan Kapar, David S. Watson, Marvin N. Wright

PMC · DOI: 10.1002/sim.70379 · 2026-02-04

## TL;DR

MissARF is a new machine learning method for filling in missing data that works well and is fast.

## Contribution

MissARF introduces a novel imputation method using adversarial random forests for efficient and accurate missing value estimation.

## Key findings

- MissARF performs comparably to state-of-the-art imputation methods in terms of quality.
- MissARF offers fast runtime and no additional costs for multiple imputation.

## Abstract

Handling missing values is a common challenge in biostatistical analyses, typically addressed by imputation methods. We propose a novel, fast, and easy‐to‐use imputation method called missing value imputation with adversarial random forests (MissARF), based on generative machine learning, that provides both single and multiple imputation. MissARF employs adversarial random forest (ARF) for density estimation and data synthesis. To impute a missing value of an observation, we condition on the non‐missing values and sample from the estimated conditional distribution generated by ARF. Our experiments demonstrate that MissARF performs comparably to state‐of‐the‐art single and multiple imputation methods in terms of imputation quality and fast runtime with no additional costs for multiple imputation.

## Full-text entities

- **Diseases:** MissARF (MESH:D000030), diabetes (MESH:D003920), prediabetes (MESH:D011236), PMM (MESH:D009800), NRMSE (MESH:D011843), ARF (MESH:D007733)
- **Species:** Mus musculus (house mouse, species) [taxon 10090], Homo sapiens (human, species) [taxon 9606]

## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12871009/full.md

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Source: https://tomesphere.com/paper/PMC12871009