# Detection of Avian Influenza H5–Specific Antibodies by Chemiluminescent Assays

## TL;DR

This study tested two assays for detecting H5 avian influenza antibodies, showing they work well with blood samples and can help assess immunity in populations.

## Contribution

The study introduces and validates two highly specific electrochemiluminescence assays for H5 avian influenza antibody detection.

## Key findings

- The assays effectively detected H5 antibodies in both serum and dried blood spots.
- They showed strong specificity and minimal cross-reactivity in human and avian samples.

## Abstract

We evaluated 2 electrochemiluminescence serologic assays to detect avian influenza H5 antibodies. The assays identified H5 antibodies from both serum and dried blood spots and had strong specificity and minimal cross-reactivity in human and avian samples. Such assays can support populationwide serologic surveys aimed at assessing population-level immunity.