# Donor Screening Failure for Strongyloides stercoralis in Solid Organ Transplantation

**Authors:** Rocio Kohan, Helena Gil-Campesino, Inés O. García Rodríguez, Magdalena Lara

PMC · DOI: 10.3201/eid3201.251483 · Emerging Infectious Diseases · 2026-01-01

## TL;DR

This paper reports two cases where kidney transplant recipients got infected with Strongyloides stercoralis from the donor despite initial negative tests.

## Contribution

The study highlights the failure of current serologic screening methods and emphasizes the need for improved protocols in high-risk populations.

## Key findings

- Donor-derived Strongyloides stercoralis infections occurred despite initial negative serologic tests.
- Retrospective testing confirmed transmission, indicating limitations in current screening practices.
- The findings stress the importance of close posttransplant surveillance and targeted protocols in endemic-risk populations.

## Abstract

We report 2 cases of donor-derived Strongyloides stercoralis infection in renal transplant recipients. Despite initial negative serologic testing in donor samples, retrospective testing confirmed transmission. This report underscores the limitations of serologic screening, the need for targeted protocols in endemic-risk populations, and the importance of close posttransplant surveillance.

## Linked entities

- **Species:** Strongyloides stercoralis (taxon 6248)

## Full-text entities

- **Genes:** CRP (C-reactive protein) [NCBI Gene 1401] {aka PTX1}, IGHE (immunoglobulin heavy constant epsilon) [NCBI Gene 3497] {aka IgE}
- **Diseases:** Histoplasma capsulatum (MESH:D006660), traumatic brain injury (MESH:D000070642), Strongyloides infection (MESH:D007239), herpes simplex virus 1 and 2 (MESH:D006561), respiratory symptoms (MESH:D012818), syphilis (MESH:D013587), toxoplasmosis (MESH:D014123), heartburn (MESH:D006356), infectious diseases (MESH:D003141), Coccidioides immitis (MESH:D003047), cytomegalovirus (MESH:D003586), subarachnoid hemorrhage (MESH:D013345), diabetic nephropathy (MESH:D003928), hypotension (MESH:D007022), eosinophilia (MESH:D004802), strongyloidiasis (MESH:D013322), Loffler syndrome (MESH:D013577), cough (MESH:D003371), gastric distension (MESH:D013272), epigastric pain (MESH:D010146), Epstein-Barr virus (MESH:D020031), asthenia (MESH:D001247), pleural and pericardial effusion (MESH:D010996)
- **Chemicals:** formalin (MESH:D005557), Formalin ethyl-acetate (-), amoxicillin/clavulanic acid (MESH:D019980), albendazole (MESH:D015766), ivermectin (MESH:D007559)
- **Species:** Human immunodeficiency virus 1 (no rank) [taxon 11676], Strongyloides stercoralis (species) [taxon 6248], Plasmodium (subgenus) [taxon 418103], Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12870113/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12870113/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12870113/full.md

---
Source: https://tomesphere.com/paper/PMC12870113