# Disseminated Nocardia ignorata Infection with Splenic and Brain Involvement in Patient with Large B-Cell Lymphoma

## TL;DR

A 79-year-old man with cancer and lung disease died from a rare Nocardia infection affecting his brain and spleen.

## Contribution

This case highlights the rare but severe manifestation of Nocardia ignorata infection in immunocompromised patients.

## Key findings

- Nocardia ignorata infection involved the brain and spleen in a patient with large B-cell lymphoma.
- The patient died despite antimicrobial therapy, underscoring the severity of disseminated Nocardia infections.

## Abstract

A 79-year-old man in the United States with large B-cell lymphoma and chronic obstructive pulmonary disease had disseminated Nocardia ignorata infection involving the brain and spleen. Despite antimicrobial therapy, he died from complications. This rare manifestation highlights the need to consider Nocardia in immunocompromised patients with central nervous system and abdominal lesions.