# Dermacentor occidentalis Ticks and Link to Rickettsia lanei Infections, California, USA

**Authors:** Will S. Probert, Chantha Kath, Naomi Putirka, Megan E.M. Saunders, Brenda Bermudez, Matthew I. Cazas, Alex Espinosa, Hannah Romo, Jill K. Hacker

PMC · DOI: 10.3201/eid3201.251261 · Emerging Infectious Diseases · 2026-01-01

## TL;DR

This study identifies Dermacentor occidentalis ticks as a likely source of Rickettsia lanei infections in California, using genome sequencing techniques.

## Contribution

The study provides the first evidence linking Dermacentor occidentalis ticks to Rickettsia lanei infections in humans.

## Key findings

- Genome sequencing confirmed Dermacentor occidentalis ticks as the likely source of Rickettsia lanei infection in a human.
- Hybridization capture-based target enrichment enabled successful genome sequencing of Rickettsia lanei from ticks.

## Abstract

Rickettsia lanei is a newly recognized spotted fever group rickettsial species that causes severe Rocky Mountain spotted fever–like illness. We used genome sequencing, enabled by hybridization capture-based target enrichment, to establish Dermacentor occidentalis ticks as the likely source of a human infection with R. lanei in California, USA.

## Linked entities

- **Diseases:** Rocky Mountain spotted fever (MONDO:0019359)
- **Species:** Dermacentor occidentalis (taxon 60254), Rickettsia lanei (taxon 3374102)

## Full-text entities

- **Diseases:** undifferentiated febrile illnesses (MESH:C580334), vectorborne diseases (MESH:D000079426), spotted (MESH:D008796), RMSF (MESH:D012373), infection (MESH:D007239), SFG rickettsioses (MESH:D000073605)
- **Chemicals:** CA6269 (-)
- **Species:** Rickettsia rickettsii (species) [taxon 783], Haemaphysalis leporispalustris (species) [taxon 34624], Homo sapiens (human, species) [taxon 9606], Rickettsia sp. (species) [taxon 789], Dermacentor occidentalis (species) [taxon 60254], Ixodida (ticks, order) [taxon 6935], CA6269 [taxon 1206091]
- **Cell lines:** HLP 7421 — Homo sapiens (Human), Chronic myelogenous leukemia, BCR-ABL1 positive, Cancer cell line (CVCL_XU99)

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12870014/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12870014/full.md

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Source: https://tomesphere.com/paper/PMC12870014