# Fatal Ehrlichia muris eauclairensis Infection in Liver Transplant Recipient, Minnesota, USA

**Authors:** Syeda Sahra, Supavit Chesdachai, Paschalis Vergidis, William Sanchez, Bobbi S. Pritt

PMC · DOI: 10.3201/eid3201.250893 · Emerging Infectious Diseases · 2026-01-01

## TL;DR

A liver transplant recipient in Minnesota died from a severe infection caused by Ehrlichia muris eauclairensis, highlighting the risks of tickborne diseases in immunocompromised individuals.

## Contribution

This is the first reported fatal case of E. muris eauclairensis infection in a liver transplant recipient.

## Key findings

- E. muris eauclairensis can cause fatal infections in immunocompromised patients.
- Tickborne infections should be considered in endemic regions for high-risk individuals.
- Healthcare providers need to be vigilant about such infections in transplant recipients.

## Abstract

Ehrlichia muris eauclairensis bacterial infections can manifest with atypical and severe symptoms in immunocompromised patients. We report a fatal case of severe ehrlichiosis caused by E. muris eauclairensis in a liver transplant recipient in Minnesota, USA. Healthcare providers must remain vigilant about tickborne infections in endemic regions, especially among immunocompromised patients.

## Linked entities

- **Diseases:** ehrlichiosis (MONDO:0016003)

## Full-text entities

- **Diseases:** lymphopenia (MESH:D008231), meningitis (MESH:D008580), diarrhea (MESH:D003967), shock (MESH:D012769), hypertrophy (MESH:D006984), febrile illness (MESH:D005334), leukopenia (MESH:D007970), QUERIES (MESH:D011778), necrosis (MESH:D009336), acute respiratory distress syndrome (MESH:D012128), ischemic injury (MESH:D017202), acute tubular injury (MESH:D001930), amnesia (MESH:D000647), edema (MESH:D004487), pancytopenia (MESH:D010198), tickborne disease (MESH:D004194), neurologic dysfunction (MESH:D009461), headache (MESH:D006261), influenza (MESH:D007251), nausea (MESH:D009325), meningitis-encephalitis (MESH:D004660), hemorrhage (MESH:D006470), EME (MESH:D016751), liver cirrhosis (MESH:D008103), fibrosis (MESH:D005355), respiratory failure (MESH:D012131), hepatocellular carcinoma (MESH:D006528), hypoxic (MESH:D002534), thrombocytopenia (MESH:D013921), seizures (MESH:D012640), alveolar damage (MESH:D055370), bacterial infections (MESH:D001424), myalgia (MESH:D063806), vomiting (MESH:D014839), infarcts (MESH:D007238), multiorgan failure (MESH:D051437), jaundice (MESH:D007565), liver allograft dysfunction (MESH:D017093), anemia (MESH:D000740), gastrointestinal symptoms (MESH:D012817), eauclairensis Infection (MESH:D007239), hyperbilirubinemia (MESH:D006932), throat congestion (MESH:C538390), Ehrlichia muris (MESH:D016873), blurred vision (MESH:D014786), confusion (MESH:D003221), rash (MESH:D005076), pulmonary edema (MESH:D011654)
- **Chemicals:** doxycycline (MESH:D004318), Hematoxylin (MESH:D006416), prednisone (MESH:D011241), cyclosporine (MESH:D016572), eosin (MESH:D004801), vancomycin (MESH:D014640), Masson's trichrome (-), glucose (MESH:D005947), sirolimus (MESH:D020123), ampicillin (MESH:D000667), cefepime (MESH:D000077723), mycophenolate (MESH:D009173)
- **Species:** Homo sapiens (human, species) [taxon 9606], Human betaherpesvirus 6 (species) [taxon 10368], Echiniscoides sp. ME (species) [taxon 1196125], Anaplasma phagocytophilum (agent of human granulocytic ehrlichiosis, species) [taxon 948], Borrelia miyamotoi (species) [taxon 47466], Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049], Ehrlichia chaffeensis (species) [taxon 945], Ixodes scapularis (blacklegged tick, species) [taxon 6945], Rickettsia (genus) [taxon 780], Ehrlichia muris subsp. eauclairensis (subspecies) [taxon 2020671], Ehrlichia muris (species) [taxon 35795], Ehrlichia ewingii (species) [taxon 947], human gammaherpesvirus 4 (Epstein Barr virus, no rank) [taxon 10376], Human immunodeficiency virus 1 (no rank) [taxon 11676], Ehrlichia (genus) [taxon 943], Cytomegalovirus (genus) [taxon 10358]

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12869986/full.md

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Source: https://tomesphere.com/paper/PMC12869986