# Reconciling Coronary Artery Calcification in the Lipid-Lowering Era

**Authors:** Shaun Khanna, Nitesh Nerlekar, Aditya Bhat

PMC · DOI: 10.1016/j.jacadv.2025.102506 · JACC: Advances · 2026-01-28

## Full-text entities

- **Genes:** PCSK9 (proprotein convertase subtilisin/kexin type 9) [NCBI Gene 255738] {aka FH3, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC1}
- **Diseases:** inflammation (MESH:D007249), coronary calcium paradox (MESH:D019320), myocardial infarction (MESH:D009203), necrosis (MESH:D009336), CAC (MESH:D003324), calcification (MESH:D002114), atherogenesis (MESH:D050197), atheroma (MESH:D058226), Acute Coronary Syndrome (MESH:D054058), coronary calcium (MESH:D003323)
- **Chemicals:** Alirocumab (MESH:C571059), calcium (MESH:D002118), Lipid (MESH:D008055)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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## References

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Source: https://tomesphere.com/paper/PMC12869863