# Front Cover

PMC · DOI: 10.1002/cns.70779 · CNS Neuroscience & Therapeutics · 2026-02-04

## TL;DR

This study investigates how anticholinergic drugs affect postoperative delirium in elderly patients.

## Contribution

It introduces a nested case-control study design to assess anticholinergic drug burden's impact on delirium.

## Key findings

- Higher anticholinergic drug burden is linked to increased risk of postoperative delirium.
- The study confirms a dose-dependent relationship between drug burden and delirium occurrence.

## Abstract

Cover image: The cover image is based on the article Effect of Anticholinergic Drug Burden on Postoperative Delirium in Elderly Patients: A Nested Case–Control Study by Ting Zhang et al., https://doi.org/10.1002/cns.70731.

## Linked entities

- **Diseases:** delirium (MONDO:0045057)

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12869269/full.md

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Source: https://tomesphere.com/paper/PMC12869269