# Does instrumentation and irrigation configuration affect intrarenal pressure during PCNL?

**Authors:** Evan Seibly, Ali Albaghli, Kyu Park, Elizabeth A. Baldwin, Ala'a Farkouh, Katya Hanessian, Nicole Mack, Cliff De Guzman, Toby Clark, Matthew Buell, Rose Leu, Kanha Shete, Sikai Song, Akin S. Amasyali, Zham Okhunov, D. Duane Baldwin

PMC · DOI: 10.1002/bco2.70164 · BJUI Compass · 2026-02-04

## TL;DR

This study examines how different tools and techniques during kidney stone surgery affect internal kidney pressure.

## Contribution

The study identifies specific configurations of instruments and irrigation that effectively control intrarenal pressure during PCNL.

## Key findings

- Using the inflow port for irrigation lowers intrarenal pressure compared to the outflow port.
- Adding suction significantly reduces intrarenal pressure in all working scenarios.
- Removing the rigid nephroscope sheath and using suction maintains the lowest pressures.

## Abstract

To measure the effects of varying configurations of nephroscope sheath, irrigation, instruments, and suction on intrarenal pressure (IRP) during percutaneous nephrolithotomy (PCNL).

Kidney and ureter 3D printed models from a deidentified patient's CT scan were placed in a plaster and foam mould, simulating the torso of a prone patient. An Amplatz sheath was inserted into the kidney model. Fourteen different rigid nephroscope sheath (RNS), irrigation, instrument and suction configurations were compared. IRP was measured in a retrograde fashion. Comparisons were performed using the Wilcoxon Signed‐Rank test followed by Bonferroni correction.

The mean IRP with and without the RNS was 19.1 and 14.7 mm Hg, respectively (p < 0.001). Using the inflow port of the RNS for irrigation created a lower IRP (19.1 mm Hg) compared to the outflow port (32.7 mm Hg; p < 0.001). Addition of suction to all working scenarios significantly reduced IRP (p < 0.001). Insertion of instruments did not significantly alter IRP.

In situations where the IRP should be low, removal of the RNS, irrigating through the inflow port, and frequent use of suction maintain the lowest pressures. If temporary increases in IRP are necessary to improve visualisation in the setting of bleeding, irrigating through the outflow port, minimising drainage and use of the RNS can be used to raise IRP.

## Full-text entities

- **Diseases:** bleeding (MESH:D006470)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12869112/full.md

## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12869112/full.md

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Source: https://tomesphere.com/paper/PMC12869112