# Myxoma of the Pulmonary Valve: A Case Report and Review of the Literature

**Authors:** Rafael Martins, José Moreira, Ana Rita Moura, Mariana Vasconcelos, Jorge Casanova

PMC · DOI: 10.7759/cureus.100790 · Cureus · 2026-01-04

## TL;DR

This paper reports a rare case of a myxoma in the pulmonary valve and discusses the challenges in diagnosing and surgically treating such tumors.

## Contribution

The paper presents a new case of pulmonary valve myxoma and emphasizes the importance of imaging and surgical techniques for successful treatment.

## Key findings

- The patient's tumor was diagnosed using echocardiography and confirmed with MRI.
- Surgical excision with cusp resection and pericardial reconstruction led to a successful recovery.
- Pulmonary valve myxomas are rare and often present with nonspecific symptoms like dyspnea.

## Abstract

Pulmonary valve myxomas are exceptionally rare cardiac tumors, with only a few reported cases in the literature, and their nonspecific presentation and uncommon location create diagnostic and surgical challenges. We report the case of a 68-year-old woman who presented with mild exertional dyspnea; transthoracic echocardiography demonstrated a 12 × 17 mm mobile mass prolapsing through the pulmonary valve, and cardiac magnetic resonance confirmed a pedunculated tumor attached to the ventricular surface of the left pulmonary cusp, without evidence of distal embolization. The patient underwent surgical excision with en bloc resection of the involved cusp and pericardial reconstruction, followed by an uneventful postoperative recovery, and histopathological analysis confirmed the diagnosis of myxoma. Pulmonary valve myxomas may manifest with obstructive, embolic, or constitutional symptoms, with dyspnea from right ventricular outflow tract obstruction representing the most frequent clinical presentation; diagnosis relies heavily on multimodality imaging, and complete surgical excision remains the definitive treatment. This case highlights the extreme rarity of pulmonary valve myxomas and underscores the value of comprehensive imaging assessment and meticulous surgical technique to achieve full tumor resection and favorable clinical outcomes.

## Linked entities

- **Diseases:** myxoma (MONDO:0044784)

## Full-text entities

- **Diseases:** Myxoma of the Pulmonary Valve (MESH:D011665), cardiac tumors (MESH:D006338), dyspnea (MESH:D004417), right ventricular outflow tract obstruction (MESH:D000092243), tumor (MESH:D009369), embolic (MESH:D004617), myxoma (MESH:D009232)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12869100/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12869100/full.md

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Source: https://tomesphere.com/paper/PMC12869100