# Comparing qualitative thematic analysis and machine-based topic modelling in the analysis of autistic and ADHD young people’s accounts of emotions

**Authors:** Steve Lukito, Lifang Li, Susie Chandler, Myrofora Kakoulidou, Georgia Pavlopoulou, Maciej Matejko, Isabel Jackson, Beta Balwani, Tiegan Boyens, Dorian Poulton, Luke Harvey-Nguyen, Amber Johnson, Daniel Stahl, Angus Roberts, Edmund J. S. Sonuga-Barke, Steve Lukito, Steve Lukito, Maciej Matejko, Beta Balwani, Tiegan Boyens, Dorian Poulton, Luke Harvey-Nguyen, Amber Johnson, Daniel Stahl, Angus Roberts, Edmund Sonuga-Barke, Susie Chandler, Andrea Danese, Johnny Downs, Eloise Funnell, Kirsty Griffiths, Myrofora Kakoulidou, Lauren Low, Umaya Prasad, Emily Simonoff, Anna Wyatt, Georgia Pavlopoulou, Jane Hurry, Sylvan Baker, Graham Moore, Dennis Ougrin, Amanda Roestorf, Rebecca Kirkbride, Jordan Altimimi, Saskia Barnes, Zoë Glen, C. J. Harris, Charlotte Hillman, Issy Jackson, Elisa Ly, Elizabeth Macauley, Anya Rose, Darren Webb, Archie Wilson

PMC · DOI: 10.1038/s41598-025-34570-7 · Scientific Reports · 2026-01-28

## TL;DR

This study compares two methods for analyzing how autistic and ADHD adolescents describe their emotions, finding that machine-based topic modeling can complement traditional qualitative analysis.

## Contribution

The study demonstrates how topic modeling can provide new insights when combined with thematic analysis in understanding neurodivergent young people's emotional experiences.

## Key findings

- Topic modeling identified 10 emotion-related topics that partially overlapped with and partially differed from themes found using thematic analysis.
- Topic modeling revealed differences in emotional experiences between school settings and other environments.
- The study suggests potential complementarity between topic modeling and thematic analysis for analyzing qualitative data.

## Abstract

Systematic analysis of interview data can provide important insights into how young people experience and interpret their emotions. Both human-led qualitative (e.g., thematic analysis) and machine-driven quantitative (e.g., natural language processing [NLP]) analytical approaches are available, but their solutions are rarely compared. Interview responses by 57 neurodivergent adolescents to questions about their emotions, previously analysed using reflexive thematic analysis (RTA), were submitted to Topic Modelling (TM). Topic labels were developed in collaboration with neurodivergent co-researchers to ground their meaning in the lived experience of neurodivergent communities. Topics were mapped to RTA themes or subthemes to examine their proximities. Topic-based cluster analysis was used to identify participant groupings with similar topic distributions. TM revealed 10 interpretable and meaningful emotion-related topics – some closely overlapping with and others differing from the RTA themes. TM topics differentiated the young people’s emotional experiences at school from those in other settings. TM and RTA resulted in overlapping and different insights into the meaning of neurodivergent young people’s accounts of their emotions. Our findings demonstrate the potential use of TM in interview analysis and might suggest a potential complementarity between the TM topics and RTA themes, to be further explored using more advanced algorithms and a more sophisticated NLP implementation.

The online version contains supplementary material available at 10.1038/s41598-025-34570-7.

## Full-text entities

- **Diseases:** ADHD (MESH:D001289), self-doubts (MESH:D012652), mental health (OMIM:603663), depression (MESH:D003866), autism (MESH:D001321), RTA (MESH:D020195), BTM (MESH:D000088562), TM (MESH:D004195)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12868839/full.md

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Source: https://tomesphere.com/paper/PMC12868839