# Review of selected mosquito-borne diseases: arboviruses (dengue, chikungunya, Zika, West Nile, Japanese encephalitis, yellow fever) and parasitic diseases (malaria, lymphatic Filariasis)

## TL;DR

This review discusses major mosquito-borne diseases, their spread, and control strategies, highlighting the impact of climate change and the need for integrated solutions.

## Contribution

The paper provides a comprehensive overview of mosquito-borne diseases, emphasizing their global impact and the challenges in control.

## Key findings

- Mosquito-borne diseases cause ~700,000 annual deaths and 17% of infectious diseases globally.
- Climate change and urbanization are expanding the geographic distribution of these diseases.
- Integrated interventions are needed to address challenges like insecticide resistance and high socioeconomic costs.

## Abstract

Mosquito-borne diseases (MBDs) are a major global public health concern, accounting for 17% of infectious diseases and causing ~700,000 annual deaths. Transmitted by Aedes, Anopheles, and Culex mosquitoes, they include viral (dengue, Zika, chikungunya), parasitic (malaria, lymphatic filariasis), and zoonotic (Japanese encephalitis) pathogens. This review outlines key MBDs’ clinical features, global distribution—concentrated in tropics but expanding due to climate change and urbanization—and transmission dynamics shaped by environmental (temperature, humidity) and ecological (urban breeding sites) factors. It also summarizes control strategies: vector management, vaccines (e.g., R21 for malaria, IXCHIQ for chikungunya), chemoprophylaxis, and novel technologies. Moreover, persistent challenges are covered, which include insecticide resistance and socioeconomic costs (e.g., $318 billion for Aedes-borne diseases since 1975), emphasizing the need for integrated interventions.