# Moral emotions in mental health: regulation and mediation

**Authors:** Angela Lu Wang

PMC · DOI: 10.3389/fpsyg.2025.1718674 · Frontiers in Psychology · 2026-01-21

## TL;DR

Moral emotions like guilt and gratitude influence mental health through both helpful and harmful processes, and understanding these can improve emotional well-being.

## Contribution

This review highlights new insights into how moral emotions regulate mental health via psychological and neural mechanisms.

## Key findings

- Moral emotions trigger adaptive and maladaptive regulatory processes that affect emotional resilience or vulnerability.
- Psychological flexibility and cognitive mechanisms mediate the link between moral emotions and mental health conditions.
- Neural correlates like the prefrontal cortices are involved in regulating moral emotions.

## Abstract

Moral emotions—such as guilt, shame, compassion, and gratitude—play a central role in shaping psychological functioning and mental health. This mini review synthesizes recent empirical and theoretical research on the regulatory roles and mediating mechanisms of moral emotions in mental health outcomes. It is demonstrated that moral emotions activate both adaptive (e.g., cognitive reappraisal, self-compassion) and maladaptive (e.g., rumination, suppression) regulatory processes that significantly influence emotional resilience or vulnerability. Additionally, psychological flexibility, emotion regulation capacity, and cognitive mechanisms such as automatic negative thoughts are identified as key mediators linking moral emotions to conditions including anxiety, depression, and subjective wellbeing. Recent findings from cognitive neuroscience are also integrated, highlighting the ventromedial and dorsomedial prefrontal cortices, as well as other structures, as neural correlates involved in the regulation of moral emotions. This review advances understanding of how moral emotions modulate mental health and to inform emotion-focused interventions.

## Linked entities

- **Diseases:** anxiety (MONDO:0005618), depression (MONDO:0002050)

## Full-text entities

- **Diseases:** depression (MESH:D003866), anxiety (MESH:D001007)

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12867822/full.md

## References

52 references — full list in the complete paper: https://tomesphere.com/paper/PMC12867822/full.md

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Source: https://tomesphere.com/paper/PMC12867822