# Ischemic preconditioning enhances energy supply during frequency speed kick test in Taekwondo athletes: A randomized crossover study

**Authors:** Ziyue Ou, Liang Yang, Dongwei Xie, Huaiyuan Zhu, Xiquan Weng, Guoqin Xu

PMC · DOI: 10.1371/journal.pone.0341780 · PLOS One · 2026-02-03

## TL;DR

This study shows that ischemic preconditioning improves energy supply and performance in taekwondo athletes during high-intensity kicking tests.

## Contribution

This is the first study to investigate ischemic preconditioning's effect on energy supply in taekwondo, revealing its potential to enhance combat sports performance.

## Key findings

- Ischemic preconditioning increased the total number of kicks during the frequency speed kick test.
- IPC improved aerobic energy supply and postexercise blood lactate clearance rate.
- Performance benefits of IPC became more pronounced with longer exercise durations.

## Abstract

This study aimed to examine the effect of ischemic preconditioning (IPC) on energy supply during sport-specific tests in male taekwondo athletes. To our knowledge, this is the first investigation of IPC’s efficacy in enhancing energy supply in a taekwondo context, underscoring its potential to optimize performance in combat sports.

Sixteen male taekwondo athletes completed a randomized crossover trial comparing an IPC condition (220 mmHg) with a sham condition (20 mmHg). Performance was evaluated via the frequency speed kick test (FSKT), and energy system contributions were quantified via the PCr–La–O₂ method. Two-way repeated-measures ANOVA and a generalized linear mixed model were used to analyze the data.

IPC significantly increased the total number of kicks in each FSKT group (98.4 ± 6.6 vs. 94.0 ± 5.5, p = 0.049, d = 0.72; 94.4 ± 7.7 vs. 89.3 ± 5.5, p = 0.036, d = 0.77; 93.1 ± 7.5 vs. 86.8 ± 6.3, p = 0.015, d = 0.90) and the aerobic energy supply (294.09 ± 50.35 vs. 270.44 ± 49.30, P = 0.031, d = 0.47). The postexercise blood lactate clearance rate was greater in the IPC trial (14.07 ± 4.94 vs. 9.14 ± 6.84, p = 0.02, d = 0.81), despite no differences in glycolytic or phosphagen contributions (49.32 ± 13.11 vs. 43.00 ± 12.25, p = 0.055).

IPC appears to enhance taekwondo performance by improving aerobic metabolism and accelerating lactate clearance, thereby promoting synergistic interactions between anaerobic and aerobic energy systems and improving energy supply. Notably, the performance benefits of IPC became more pronounced as exercise duration increased, suggesting a cumulative ergogenic effect during prolonged high-intensity activity.

## Full-text entities

- **Genes:** KNG1 (kininogen 1) [NCBI Gene 3827] {aka BDK, BK, HAE6, HK, HMWK, KNG}
- **Diseases:** fatigue (MESH:D005221), acidosis (MESH:D000138), IPC (MESH:D002545), hypertension (MESH:D006973), ischemic injury (MESH:D017202), anxiety (MESH:D001007), metabolic disorders (MESH:D008659), tingling (MESH:D010292), inflammatory (MESH:D007249), numbness (MESH:D006987), depression (MESH:D003866), ischemia (MESH:D007511), cardiovascular diseases (MESH:D002318)
- **Chemicals:** ATP-CP (-), nitric oxide (MESH:D009569), lactate (MESH:D019344), adenosine (MESH:D000241), glucose (MESH:D005947), La (MESH:D007811), CO2 (MESH:D002245), acetyl-CoA (MESH:D000105), SHAM (MESH:C005703), creatine (MESH:D003401), alcohol (MESH:D000438), H+ (MESH:D006859), caffeine (MESH:D002110), ATP (MESH:D000255), phosphagen (MESH:D010725), O2 (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606], Rattus norvegicus (brown rat, species) [taxon 10116]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12867267/full.md

## References

65 references — full list in the complete paper: https://tomesphere.com/paper/PMC12867267/full.md

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Source: https://tomesphere.com/paper/PMC12867267