# Diet and stones: Associations from a large, population-representative study of urolithiasis and renal colic-like pain symptoms in Poland

**Authors:** Jakub Szymanski, Przemyslaw Dudek, Pawel Rajwa, Wojciech Krajewski, Piotr Bryniarski, Katarzyna Krzanowska, Piotr Chlosta, Mikolaj Przydacz

PMC · DOI: 10.1371/journal.pone.0333733 · PLOS One · 2026-02-03

## TL;DR

This study explores how diet and body weight affect kidney stone and pain symptoms in Poland, finding strong links with fast food and other dietary choices.

## Contribution

The study provides the first comprehensive population-based analysis of urolithiasis and renal colic-like pain symptoms in Central and Eastern Europe.

## Key findings

- Overweight, obese, and underweight individuals have higher prevalence of urolithiasis and renal colic-like pain symptoms.
- Fast food consumption nearly triples the risk of urolithiasis and increases pain symptoms by 64.5%.
- Dietary factors like beef, legumes, soy, soda, and processed meat are significant predictors of these conditions.

## Abstract

Urolithiasis and renal colic-like pain symptoms are prevalent conditions influenced by many factors, including diet. Regional assessments, particularly in culturally distinct areas, are essential for understanding specific risk patterns and for developing targeted public health strategies and educational programs. Therefore, the aim of this study was to identify associations between urolithiasis, renal colic-like pain symptoms, and diet, including body weight, in a representative sample of adult Poles.

A population-representative online survey of 10,029 adults was conducted using census-based quota sampling to ensure balanced representation by age, sex, and residence across all 16 Polish voivodships, including urban and rural areas.

Normal-weight individuals had the lowest prevalence of urolithiasis and renal colic-like pain symptoms; overweight, obese, and underweight persons had higher prevalences (p < 0.001). Eighteen food items were linked to urolithiasis, with beef, legumes, soy, soda, coffee, and fast food found as independent predictors of urolithiasis. Nineteen foods were associated with renal colic-like pain symptoms, with processed meat, soy, legumes, fruit juices, soda, instant meals, and fast food identified as independent predictors of symptoms. Fast food showed the strongest effects, with daily consumption nearly tripling the risk of urolithiasis (OR=2.847; p = 0.001) and increasing renal colic-like pain symptoms by 64.5% (OR=1.645; p = 0.006) compared with no consumption of fast food.

This study provides the first comprehensive, population-based analysis of urolithiasis, renal colic-like pain symptoms, and dietary patterns in Central and Eastern Europe. Our findings demonstrate that both conditions are influenced by body weight and a range of dietary factors.

## Linked entities

- **Diseases:** urolithiasis (MONDO:0024647)

## Full-text entities

- **Diseases:** anorexia nervosa (MESH:D000856), obese (MESH:D009765), Stone disease (MESH:D007669), urinary stone (MESH:D014545), hypercalciuric (MESH:C562793), hydronephrosis (MESH:D006869), vomiting (MESH:D014839), eating disorders (MESH:D001068), hypertension (MESH:D006973), underweight (MESH:D013851), stone formation (MESH:D058426), cramp (MESH:D009120), hyperchloremic acidosis (MESH:D000138), like symptoms (MESH:D012816), Urolithiasis (MESH:D052878), nausea (MESH:D009325), Diabetes (MESH:D003920), metabolic disturbances (MESH:D024821), hypokalemia (MESH:D007008), bladder and prostate cancer (MESH:D011471), depression (MESH:D003866), electrolyte imbalances (MESH:D014883), malnourished (MESH:D044342), dehydration (MESH:D003681), overweight (MESH:D050177), like pain (MESH:D010146), refeeding syndrome (MESH:D055677), Renal colic (MESH:D056844), chronic kidney disease (MESH:D051436), anxiety (MESH:D001007), back pain (MESH:D001416), Digestive and Kidney Diseases (MESH:D007674), diarrhea (MESH:D003967), calcium oxalate stones (MESH:C563477), metabolic abnormalities (MESH:D008659)
- **Chemicals:** calcium (MESH:D002118), cafestol (MESH:C053400), salt (MESH:D012492), magnesium (MESH:D008274), phytates (MESH:D010833), sugar (MESH:D000073893), ammonium (MESH:D064751), kahweol (MESH:C053401), sodium (MESH:D012964), Fructose (MESH:D005632), ammonium urate (-), Citrate (MESH:D019343), purine (MESH:C030985), oxalate (MESH:D010070), uric acid (MESH:D014527), vitamin C. (MESH:D001205), potassium (MESH:D011188), Carbohydrates (MESH:D002241), cholesterol (MESH:D002784), water (MESH:D014867)
- **Species:** Oryza sativa (Asian cultivated rice, species) [taxon 4530], Theobroma cacao (cacao, species) [taxon 3641], Avena sativa (cultivated oat, species) [taxon 4498], Homo sapiens (human, species) [taxon 9606], Spinacia oleracea (spinach, species) [taxon 3562]

## Full text

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## Figures

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## References

51 references — full list in the complete paper: https://tomesphere.com/paper/PMC12867237/full.md

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Source: https://tomesphere.com/paper/PMC12867237