# Pheochromocytoma Presenting With Paroxysmal Hypertensive Crises in a Previously Healthy Woman: A Case Report

## TL;DR

A previously healthy woman experienced severe high blood pressure episodes due to a rare adrenal tumor, which was successfully treated with surgery.

## Contribution

This case report highlights the importance of early diagnosis of pheochromocytoma in middle-aged patients with unexplained paroxysmal hypertension.

## Key findings

- A 41-year-old woman with no known health issues was diagnosed with pheochromocytoma after presenting with severe hypertension and adrenergic symptoms.
- Successful laparoscopic adrenalectomy normalized her blood pressure and eliminated the need for antihypertensive therapy.
- The case underscores the need for timely diagnosis and treatment to prevent life-threatening complications.

## Abstract

Pheochromocytomas are rare catecholamine-secreting neuroendocrine tumors that typically present with episodic headaches, sweating, palpitations, and hypertension. Delayed diagnosis, although uncommon, can lead to severe cardiovascular complications.

We report the case of a 41-year-old woman with no known comorbidities who presented with a 20-day history of recurrent episodes of severe hypertension, with blood pressure reaching 220/110 mmHg, accompanied by headaches, palpitations, tremor, and diaphoresis. Biochemical evaluation revealed elevated urinary metanephrines and normetanephrines. Abdominal computed tomography (CT) demonstrated a 6-cm left adrenal mass.

After appropriate preoperative alpha- and beta-adrenergic blockade, the patient underwent a successful laparoscopic left adrenalectomy. Histopathology confirmed pheochromocytoma. Postoperatively, her blood pressure normalized, antihypertensive therapy was discontinued, and she was advised to undergo genetic testing and regular follow-up.

Early recognition of pheochromocytoma is essential, as delayed diagnosis can result in severe and potentially life-threatening complications. This case emphasizes the importance of considering pheochromocytoma in middle-aged patients presenting with unexplained paroxysmal hypertension and adrenergic symptoms, as timely surgical management can be curative.