# Screening and risk factor analysis of osteoporosis in elderly patients with chronic heart failure

**Authors:** Tiantian Tang, Namin Ma, Shilin Yu, Shijie Peng, Wenyan Liu, Yahui Geng

PMC · DOI: 10.1186/s40001-025-03665-2 · European Journal of Medical Research · 2026-01-03

## TL;DR

This study finds that over half of elderly patients with heart failure also have osteoporosis, with risk factors including low BMI, poor nutrition, diabetes, and reduced mobility.

## Contribution

The study identifies specific independent risk factors for osteoporosis in elderly patients with chronic heart failure.

## Key findings

- Osteoporosis prevalence was 61.95% among 205 elderly heart failure patients.
- Low BMI, diabetes, malnutrition, and poor daily activity scores are independent risk factors for osteoporosis.
- Early screening and intervention for these risk factors are recommended for heart failure patients.

## Abstract

To evaluate osteoporosis in hospitalized elderly patients with chronic heart failure and analyze its risk factors.

A total of 230 elderly patients with heart failure from October 2021 to October 2022 were included in this study. Bone mineral density (BMD) was measured via dual-energy X-ray absorptiometry, and the incidence of osteoporosis was analyzed. T tests or Χ2 tests were used to compare the influence of each factor on the detection rate, and multivariate logistic regression analysis was used to analyze the independent risk factors.

The prevalence of osteoporosis was 61.95% in 205 elderly patients with heart failure. The lower the BMI is, the worse the heart function, and the lower the score of daily activity, the higher the detection rate of osteoporosis in heart failure patients; the incidence of osteoporosis was greater in patients with heart failure accompanied by diabetes, cognitive impairment, chronic kidney disease, and malnutrition (P < 0.05). Multiple logistic regression analysis revealed that BMI, activities of daily living, diabetes mellitus, and malnutrition were independent risk factors (P < 0.05).

Osteoporosis is common in hospitalized elderly patients with heart failure. Screening for osteoporosis should be carried out as early as possible to intervene in risk factors in time. Poor nutritional status, low body weight, decreased living ability, and diabetes mellitus were the independent risk factors for osteoporosis (P < 0.05).

## Linked entities

- **Diseases:** osteoporosis (MONDO:0005298), diabetes mellitus (MONDO:0005015), chronic kidney disease (MONDO:0005300)

## Full-text entities

- **Diseases:** malnutrition (MESH:D044342), diabetes (MESH:D003920), cognitive impairment (MESH:D003072), heart failure (MESH:D006333), Osteoporosis (MESH:D010024), chronic kidney disease (MESH:D051436)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC12866196