# Serous Ovarian Cancer Following Opportunistic Bilateral Salpingectomy **Authors:** Ramlogan Sowamber, Alice J. Mei, Paramdeep Kaur, Julianne McLeod, Emily McKay, Alex Lukey, Jamie Bakkum-Gamez, Natalia Buza, Paul A. Cohen, Kyle Devins, Rhonda Farrell, Christine Garcia, Blake Gilks, Ellen Goode, Anjelica Hodgson, Brooke Howitt, Pei Hui, Jutta Huvila, Anthony Karnezis, Kianoosh Keyhanian, Mary Kinloch, Martin Köbel, Felix K. F. Kommoss, Lawrence Kushi, Janice S. Kwon, Kara Long-Roche, Anais Malpica, Jessica N. McAlpine, Dianne Miller, Esther Oliva, Andrea Palicelli, Aleksandra Paliga, Carlos Parra-Herran, Celeste Leigh Pearce, Sharnel Perera, Jurgen M. Piek, Haiyan Qiu, Joseph Rabban, Robert Rome, Miranda Steenbeek, Rebecca Stone, Aline Talhouk, Kristin M. Tischer, Britton Trabert, Penelope M. Webb, John R. Zalcberg, David G. Huntsman, Gillian E. Hanley PMC · DOI: 10.1001/jamanetworkopen.2025.57267 · JAMA Network Open · 2026-02-02 ## TL;DR This study examines how opportunistic bilateral salpingectomy in Canada affects the risk of high-grade serous ovarian cancer. ## Contribution The study provides empirical evidence on the impact of salpingectomy on serous ovarian cancer risk in a Canadian cohort. ## Key findings - Opportunistic bilateral salpingectomy is associated with a reduced risk of high-grade serous carcinoma. - The procedure may serve as an effective preventive strategy for ovarian cancer in women undergoing pelvic surgery. ## Abstract This cohort study evaluates the reduction in risk of high-grade serous carcinoma among women undergoing opportunistic bilateral salpingectomy in Canada. ## Linked entities - **Diseases:** ovarian cancer (MONDO:0005140) ## Full-text entities - **Diseases:** cancer (MESH:D009369), endometrioid ovarian carcinoma (MESH:D010051), HGSC (MESH:D008228), OBS (MESH:D009894), breast cancer (MESH:D001943), serous carcinoma (MESH:D018297), low-grade serous carcinoma (MESH:D015451) - **Species:** Homo sapiens (human, species) [taxon 9606] ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12865655/full.md ## Figures 1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12865655/full.md ## References 6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12865655/full.md --- Source: https://tomesphere.com/paper/PMC12865655