# Renal profile and the associated outcome of patients with acute kidney injury undergoing dialysis in Renal Unit at a Tertiary Healthcare Facility in Western Kenya

**Authors:** Rodgers Norman Demba, Sylviah Mweyeli Aradi

PMC · DOI: 10.4314/ahs.v25i1.30 · African Health Sciences · 2025-03-01

## TL;DR

This study examines the kidney function and outcomes of patients with acute kidney injury undergoing dialysis in a Kenyan hospital.

## Contribution

The study identifies renal profiles and outcomes of AKI patients in a specific Kenyan healthcare setting.

## Key findings

- AKI patients had a 26% mortality rate after dialysis initiation.
- Majority of AKI patients died within or after one month of diagnosis.

## Abstract

Acute Kidney Injury (AKI) is characterized by sudden decline or loss of kidney function.

This study aimed to determine the renal profile and the outcome of AKI patients undergoing dialysis.

Retrospective cohort study was conducted from January 2015 to December 2021.

Of the 69 AKI patients enrolled in this study, 33 (47.8%) were men, and 36 (52.2%) were women. Majority (55.56%; 10) of the AKI patients died within one month of diagnosis, 44.44% (8) died after one month. Independent predictors of survival were creatinine level (adjusted hazard ratio= 20.54, 95% CI: 0.15, 2862.17; P = 0.23), urea level (adjusted hazard ratio= 0.56, 95% CI: 0.05, 6.78; P = 0.65), phosphate level (adjusted hazard ratio= 5.94, 95% CI: 0.51, 69.57; P = 0.16), calcium level (adjusted hazard ratio= 0.31, 95% CI: 0.04, 2.67; P = 0.29), sodium level (adjusted hazard ratio= 0.53, 95% CI: 0.27, 10.21; P = 0.67), potassium level (adjusted hazard ratio= 5.3, 95% CI: 0.38, 73.56; P = 0.21), chloride level (adjusted hazard ratio= 0.23, 95% CI: 0.03, 1.66; P = 0.15).

AKI patients had a mortality rate of 26% after initiation of dialysis.

## Linked entities

- **Diseases:** Acute Kidney Injury (MONDO:0002492)

## Full-text entities

- **Diseases:** kidney (MESH:D007674), AKI (MESH:D058186)
- **Chemicals:** chloride (MESH:D002712), phosphate (MESH:D010710), potassium (MESH:D011188), urea (MESH:D014508), creatinine (MESH:D003404), sodium (MESH:D012964), calcium (MESH:D002118)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12865084/full.md

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Source: https://tomesphere.com/paper/PMC12865084