# Value of cerebrovascular hemodynamics and thromboelastogram-related parameters in evaluating the effect of Naomai Jiejing Decoction on the rehabilitation of patients with aneurysmal subarachnoid hemorrhage

## TL;DR

This study examines how cerebrovascular hemodynamics and blood clotting parameters help assess the effectiveness of a traditional Chinese medicine treatment for aneurysmal subarachnoid hemorrhage patients' rehabilitation.

## Contribution

The study introduces the use of hemodynamic and thromboelastogram parameters to evaluate the efficacy of Naomai Jiejing Decoction in aneurysmal subarachnoid hemorrhage rehabilitation.

## Key findings

- Patients treated with Naomai Jiejing Decoction had significantly lower hemodynamics values compared to the control group.
- Higher hemodynamics and thromboelastogram values were linked to poor rehabilitation outcomes in treated patients.
- Monitoring these parameters correlates with better rehabilitation outcomes in aneurysmal subarachnoid hemorrhage patients.

## Abstract

To explore the value of cerebrovascular hemodynamic and thromboelastogram-related parameters in evaluating the effect of Naomai Jiejing Decoction (NJD) on the rehabilitation of patients with Aneurysmal subarachnoid hemorrhage (aSAH).

This article is observational studies. This study compared cerebrovascular hemodynamics, thromboelastogram results, and rehabilitation outcomes between a research group (treated with Naomai Jiejing Decoction) and a control group (not treated with Naomai Jiejing Decoction) of 160 patients with Aneurysmal subarachnoid hemorrhage. Logistic regression analysis explored associations between poor rehabilitation outcomes and hemodynamic/thromboelastogram-related parameters in the research group.

At 12 months after operation, the measured hemodynamics values were lower in research group than those in control group, and the differences were statistically significant (P<0.05). Patients with good rehabilitation outcomes had lower measured hemodynamics values than those with poor rehabilitation outcomes. The results of Logistic regression analysis showed that the high values in hemodynamics and thromboelastogram examinations were risk factors for poor rehabilitation outcomes in research group (P<0.05).

Monitoring cerebrovascular hemodynamic and thromboelastogram-related parameters in patients with Aneurysmal subarachnoid hemorrhage receiving Naomai Jiejing Decoction treatment can offer valuable prognostic and therapeutic insights, with improvements correlating to better rehabilitation outcomes, underscoring their significance in assessing intervention effectiveness.