# SHI: a framework for spatial harmonic imaging

**Authors:** Jorge Luis Beltran Diaz, Jan G. Korvink, Danays Kunka

PMC · DOI: 10.1038/s41598-026-37029-5 · Scientific Reports · 2026-01-29

## TL;DR

SHI is a new software framework that improves spatial harmonic X-ray imaging by streamlining data acquisition and processing.

## Contribution

SHI introduces a high-performance open-source framework for spatial harmonic imaging with streamlined data workflows and higher-order harmonic extraction.

## Key findings

- SHI enables efficient organization, processing, and visualization of spatial harmonic imaging data.
- Lower-resolution images from SHI allow faster CT reconstruction with fewer projections while preserving key features.
- The framework improves experimental robustness and retrieves refraction and scattering information.

## Abstract

Despite the growing interest in multicontrast X-ray imaging, spatial harmonic imaging remains limited by a lack of specialized computational resources. In this paper, we present SHI, a high-performance software framework that covers the range from data acquisition to processing in spatial harmonic imaging experiments. SHI is an open-source software package that facilitates the acquisition of precise measurement data and streamlines the workflow, ensuring that data can be efficiently organized, processed, and visualized, leading to high quality results. In addition, SHI includes higher-order harmonic extraction. Preliminary results show that spatial harmonic imaging improves experimental robustness and retrieves refraction and scattering information, albeit with reduced resolution. However, using these lower-resolution images enables faster CT reconstruction with fewer projections, while preserving essential sample features and allowing a substantial reduction in exposure levels. This research focuses on the acquisition methodology and the subsequent data processing for contrast retrieval and multicontrast computed tomography.

## Full-text entities

- **Genes:** bright (bright) [NCBI Gene 247929], dk (dark on 3) [NCBI Gene 246855]
- **Diseases:** Computed (MESH:C000719218)
- **Chemicals:** polymer (MESH:D011108), Au (MESH:D006046)

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## Figures

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## References

1 references — full list in the complete paper: https://tomesphere.com/paper/PMC12864874/full.md

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Source: https://tomesphere.com/paper/PMC12864874