# Medicinal Plants and Lead Phytomolecules as Immunomodulators: An Updated Review

## TL;DR

This review explores how medicinal plants and their compounds can modulate the immune system to treat various immune-related conditions.

## Contribution

The paper provides an updated review of medicinal plants and their phytomolecules as immunomodulators.

## Key findings

- Medicinal plants like Curcuma longa and Camellia sinensis are used to treat immune disorders.
- Phytoconstituents from these plants have mechanisms that modulate immune responses.
- They offer fewer side effects compared to conventional treatments.

## Abstract

All therapeutic interventions aimed at modulating the immune response to pathogens, self‐antigens, carcinogens, or xenogeneic antigens are referred to as immunomodulation, which either prevents hyperactivation or restores the appropriate response of the immune system. Since antiquity, medicinal plants have been used as a source of immune‐boosting medicines with fewer side effects. These medicinal plants, for example, Curcuma longa, Camellia sinensis, Artemisia annua, and Andrographis paniculata, have been used to treat immune system disorders such as multiple sclerosis, psoriasis, lupus, and organ transplantation. Herein, we review the currently accessible medicinal plants, their phytoconstituents, and underlying mechanisms of immunomodulation.